Advances in phototheranostic agents: From imaging to targeted therapy

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dc.authorscopusidMeisam Samadzadeh / 58513212300
dc.authorscopusidHadi Noei / 58513454900
dc.authorscopusidAli Zarrabi / 23483174100
dc.authorwosidMeisam Samadzadeh / IZO-6926-2023
dc.authorwosidHadi Noei / IZP-0266-2023
dc.authorwosidAli Zarrabi / GSA-3718-2022
dc.contributor.authorSamadzadeh, Meisam
dc.contributor.authorKhosravi, Arezoo
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorNoei, Hadi
dc.contributor.authorSivakumar, Ponnurengam Malliappan
dc.contributor.authorIravani, Siavash
dc.contributor.authorZarrabi, Ali
dc.date.accessioned2025-04-18T08:19:53Z
dc.date.available2025-04-18T08:19:53Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümü
dc.description.abstractThe recent evolution of phototheranostic agents represents a groundbreaking intersection of diagnostic imaging and targeted therapy, particularly in oncology. This review aims to elucidate the recent advances in phototheranostic agents, highlighting their dual functionality in imaging and targeted therapy. Despite significant progress, several challenges persist, including the optimization of agent specificity, light penetration in tissues, and the potential for off-target effects. The variability in tumor microenvironments presents a significant obstacle, complicating the development of universal phototheranostic agents. Moreover, concerns regarding the long-term stability, potential toxicity, and biocompatibility of these agents necessitate thorough evaluation and optimization. Notably, the complexity of designing nanoparticles that can effectively deliver both imaging and therapeutic modalities poses additional hurdles. Future perspectives in this field emphasize the need for innovative strategies to enhance agent stability, biocompatibility, and targeted delivery. Furthermore, ongoing research focuses on the development of novel light-based techniques and the exploration of combination therapies to improve treatment efficacy. By addressing these challenges, the potential of phototheranostic agents to transform personalized cancer therapy becomes increasingly promising. This review serves as a comprehensive overview of the current landscape, challenges, and future directions in phototheranostic research, ultimately aiming to inform and inspire further investigation in this dynamic field. © 2025 Elsevier Ltd
dc.identifier.citationSamadzadeh, M., Khosravi, A., Zarepour, A., Noei, H., Sivakumar, P. M., Iravani, S., & Zarrabi, A. (2025). Advances in phototheranostic agents: From imaging to targeted therapy. Materials Today Chemistry, 43, 102516.
dc.identifier.doi10.1016/j.mtchem.2025.102516
dc.identifier.issn24685194
dc.identifier.scopus2-s2.0-85214832106
dc.identifier.scopusqualityQ1
dc.identifier.urihttp://dx.doi.org/10.1016/j.mtchem.2025.102516
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6546
dc.identifier.volume43
dc.identifier.wosWOS:001401016800001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.institutionauthorSamadzadeh, Meisam
dc.institutionauthorNoei, Hadi
dc.institutionauthorZarrabi, Ali
dc.institutionauthoridMeisam Samadzadeh / 0009-0007-2780-6361
dc.institutionauthoridHadi Noei / 0000-0002-1977-1994
dc.institutionauthoridAli Zarrabi / 0000-0003-0391-1769
dc.language.isoen
dc.publisherElsevier Ltd.
dc.relation.ispartofMaterials Today Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Öğrenci
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectİmaging
dc.subjectPhotodynamic Therapy
dc.subjectPhototheranostic Agents
dc.subjectPhotothermal Therapy
dc.subjectTargeted Therapy
dc.titleAdvances in phototheranostic agents: From imaging to targeted therapy
dc.typeArticle

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