Cytotoxicity screening of some Turkish plants against renal cancer cells

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dc.contributor.authorMihoğlugil, F.
dc.contributor.authorAkalgan, D.
dc.contributor.authorTosun, F.
dc.date.accessioned2024-05-19T14:33:46Z
dc.date.available2024-05-19T14:33:46Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractIn this contribution, we performed cytotoxicity screening of 51 extracts from 17 plant species, representing 14 families growing in Turkey. Cytotoxic activities of the dichloromethane, ethyl acetate, and methanol extracts of the plants were investigated against the renal (A498 and U031) cancer cell lines. 28 extracts exhibited more than 50% growth inhibition at a 25 ug/mL concentration on both renal cancer A498 and UO31 cell lines. The extracts showed higher activity against UO31 cells than A498 cells. The dichloromethane extract of the aerial parts of Scabiosa columbaria ssp. columbaria showed the highest cytotoxic activity with 64% inhibition at a 25 ug/mL concentration on the renal cancer UO31 cell line. The methanol extract of the aerial parts of Epilobium minutiflorum showed the highest cytotoxic activity with 63% inhibition at a 25 ug/mL concentration on the renal cancer A498 cell line. © 2023 Marmara UniversityPress.en_US
dc.identifier.doi10.29228/jrp.346
dc.identifier.endpage641en_US
dc.identifier.issn2630-6344
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85151358720en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage636en_US
dc.identifier.trdizinid1177566en_US
dc.identifier.urihttps://doi.org/10.29228/jrp.346
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1177566
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4332
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherMarmara Universityen_US
dc.relation.ispartofJournal of Research in Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCytotoxic Activityen_US
dc.subjectRenal Canceren_US
dc.subjectScabiosa Columbaria Ssp. Columbariaen_US
dc.subjectTurkish Plantsen_US
dc.titleCytotoxicity screening of some Turkish plants against renal cancer cellsen_US
dc.typeArticleen_US

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