The relationship between vitamin C and oxidative status in periodontitis: A case-control study

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Bayrakol Medical Publisher

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Aim: A co-factor for reactions including collagen hydroxylation, vitamin C prevents oxidative damage to DNA and proteins and may be associated with oxidative stress in periodontitis. This study was designed to test the hypothesis that vitamin C is inversely related to oxidative stress markers in individuals with periodontitis.Material and Methods: This study was conducted with 25 individuals with periodontitis and 24 individuals without periodontitis. Vitamin C intake of participants was determined using a valid food frequency questionnaire, and plasma ascorbic acid levels of participants were measured using high-performance liquid chromatography. Total antioxidant status and total oxidant status were measured in serum and saliva samples, and the oxidative stress index was calculated. Lucigenin-enhanced chemiluminescence assays determined superoxide radicals in saliva.Results: Vitamin C intake in patients with periodontitis was found to be lower than in the control group (124.68 mg/d and 176.71 mg/d, p=0.003, respectively). The plasma ascorbic acid levels and total oxidant status (p=0.03,r=-0.42) and superoxide radical levels (p=0.01,r=-0.53) were inversely correlated in patients with periodontitis.Discussion: Dietary vitamin C intake in patients with periodontitis was lower than in healthy individuals; vitamin C intake may be inversely related to oxidative stress which is the underlying cause of periodontitis.

Açıklama

Anahtar Kelimeler

Periodontitis, Antioxidants, Oxidative Stress, Vitamin C, Periodontal Disease

Kaynak

Annals of Clinical and Analytical Medicine

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

14

Sayı

7

Künye