RT-PCR cycle threshold (Ct) values predicting COVID-19 patients' outcome
| dc.contributor.author | İğnak, Seyda | |
| dc.contributor.author | Yalçın, Demet | |
| dc.contributor.author | Çeçen, Olida | |
| dc.contributor.author | Sonkaya, Muhammed Mert | |
| dc.contributor.author | Uluışık, Işılsu Ezgi | |
| dc.contributor.author | Demirel, Özlem Unay | |
| dc.date.accessioned | 2022-09-20T06:52:46Z | |
| dc.date.available | 2022-09-20T06:52:46Z | |
| dc.date.issued | 2022 | en_US |
| dc.department | İstinye Üniversitesi, Hastane | en_US |
| dc.description.abstract | Aim: Clinical presentation of COVID-19 ranges from asymptomatic to fatal cases. Therefore, predictability of prognosis gains importance in managing the disease. The aim of this study is to investigate the relation between RT-PCR cycle threshold (Ct) values and the clinical severity of COVID-19 infection. Material and Methods: A retrospective study was conducted among 1224 COVID-19 patients. A scoring system, which is designed by the World Health Organization was used to classify patients by means of their clinical status. Results: The cut-off for Ct value in ROC curves was 21.52 at the point, when the COVID-19 patient clinic is shifting from ambulatory to hospitalized (79.7% sensitivity, 69% specificity). A significant weak positive correlation was found between age and WHO Score (r= .238 p<0.01) and a significant weak negative correlation was found between Ct value and WHO Score (r=-.068 p<0.05) in COVID-19 patients. Discussion: Patients with lower RT-PCR Ct values were more likely to go through the disease more severely due to higher virulence. Reporting of numerical Ct values may help clinicians in terms of prognosis. | en_US |
| dc.identifier.citation | Ignak, S., Yalcin, D., Cecen, O., Sonkaya, M. M., Uluisik, I. E., Demirel, O. U. (2022). RT-PCR cycle threshold (Ct) values predicting COVID-19 patients' outcome. Annals of Clinical and Analytical Medicine, 13(8), 882-886. | en_US |
| dc.identifier.doi | 10.4328/ACAM.21145 | en_US |
| dc.identifier.endpage | 886 | en_US |
| dc.identifier.issn | 2667-663X | en_US |
| dc.identifier.issue | 8 | en_US |
| dc.identifier.startpage | 882 | en_US |
| dc.identifier.uri | https://doi.org/10.4328/ACAM.21145 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12713/3165 | |
| dc.identifier.volume | 13 | en_US |
| dc.identifier.wos | WOS:000852590900011 | en_US |
| dc.identifier.wosquality | N/A | en_US |
| dc.indekslendigikaynak | Web of Science | en_US |
| dc.institutionauthor | Yalçın, Demet | |
| dc.language.iso | en | en_US |
| dc.publisher | BAYRAKOL | en_US |
| dc.relation.ispartof | ANNALS OF CLINICAL AND ANALYTICAL MEDICINE | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | PCR | en_US |
| dc.subject | Cycle Threshold | en_US |
| dc.subject | COVID-19 | en_US |
| dc.subject | SARS CoV-2 | en_US |
| dc.title | RT-PCR cycle threshold (Ct) values predicting COVID-19 patients' outcome | en_US |
| dc.type | Article | en_US |
