Factors affecting mortality in COVID-19

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dc.authorscopusidAli Sait Kavaklı / 57192362478
dc.authorwosidAli Sait Kavaklı / L-5699-2016
dc.contributor.authorÖzer, Burcu
dc.contributor.authorYıldız, Ülkü Arslan
dc.contributor.authorKavaklı, Ali Sait
dc.contributor.authorCengiz, Melike
dc.contributor.authorTemel, Hakan
dc.contributor.authorYılmaz, Murat
dc.date.accessioned2025-04-17T07:31:08Z
dc.date.available2025-04-17T07:31:08Z
dc.date.issued2025
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractObjective: Determining the factors affecting mortality may be pivotal in terms of improving survival in the coronavirus disease-2019 (COVID-19). The aim of this study was to determine the demographic, clinical and laboratory characteristics of COVID-19 patients and the factors affecting intensive care unit (ICU) mortality. Materials and Methods: It was designed as a retrospective cohort study in which patients with a diagnosis of COVID-19 hospitalized in the ICU. The clinical and laboratory parameters were compared between cohorts with mortality and those with survival cohorts. Univariate and multivariate logistic regression analyses were performed for the effect profiles of the parameters on mortality. Results: The mortality of 58.6% was similar for the three pandemic waves or selected time intervals (p=0.245). Presence of comorbid disease, age, COVID-19 related complications, admission, acute physiology and chronic health evaluation II (APACHE II) and sequential organ failure assessment (SOFA) scores were significantly higher in the mortality cohort (p<0.001). The factors influencing mortality according to the multivariate logistic regression model were hypertension, malignancy (solid and hematologic), neurological illness, age, APACHE-II and SOFA scores, and neutrophil to lymphocyte ratio. Conclusion: The patients with these risk factors should be monitored with greater caution in terms of the timing and duration of ICU care.
dc.identifier.citationÖzer, B., Yıldız, Ü. A., Kavaklı, A. S., Cengiz, M., Temel, H., & Yılmaz, M. (2025). COVID-19’da Mortaliteyi Etkileyen Faktörler.
dc.identifier.doi10.4274/tybd.galenos.2024.50469
dc.identifier.endpage52
dc.identifier.issn2602-2974
dc.identifier.issue1
dc.identifier.startpage38
dc.identifier.urihttp://dx.doi.org/10.4274/tybd.galenos.2024.50469
dc.identifier.urihttps://hdl.handle.net/20.500.12713/6124
dc.identifier.volume23
dc.identifier.wosWOS:001433479600001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorKavaklı, Ali Sait
dc.institutionauthoridAli Sait Kavaklı / 0000-0001-5263-7183
dc.language.isoen
dc.publisherGalenos publishing house
dc.relation.ispartofTurkish journal of intensive care-Türk yoğun bakım dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCOVID-19
dc.subjectMortality
dc.subjectIntensive Care Unit
dc.titleFactors affecting mortality in COVID-19
dc.typeArticle

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