Using small size grafts in live donor liver transplantation: is size important?

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dc.contributor.authorEren, E.
dc.contributor.authorDinçkan, A.
dc.date.accessioned2024-05-19T14:34:01Z
dc.date.available2024-05-19T14:34:01Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractPurpose: In living donor liver transplantation, it is preferred that the ratio of the weight of the graft to the weight of the recipient (GRWR) be higher than 0.8%. We aimed to compare recipients with a GRWR greater than 0.8% and those with a small GRWR regarding post-transplant complications and outcomes. Materials and methods: Data of the patients who had undergone living donor liver transplant surgery in İstinye University Hospital Liver Transplant Unit between January 2017 and July 2022 were reviewed. The study group patients were classified as GRWR<0.8% (Group 1), GRWR 0.8-1% (Group 2), and GRWR>1% (Group 3) and compared regarding clinical data, complications, and mortality rates. Results: Liver transplant recipients from 220 living donors were included. The mean recipient age was 53.6 (18-79). The comparative analysis between Group 1 (n=29), Group 2 (n=70), and Group 3 (n=121) revealed significant differences concerning the rates of bile leak and the length of hospital stay (p=0.033, p<0.05). Bile leak rates were 7.4% in Group 1, 6% in Group 2, and 0.8% in Group 3. The bile leakage rate was significantly lower in Group 3 than in Groups 1 and 2 (p=0.041, p<0.05). The medians of hospitalization periods were 18 (7-40) days, 15 (5-46) days, and 16 (1-130) days in groups 1, 2, and 3. In addition, the median length of stay was higher in Group 1 than in groups 2 and 3 (p=0.033). In terms of other parameters, the three groups gave similar results. Conclusion: Although a GRWR value of lower than 0.8 seems as a factor causing prolonged hospital stay, and a GRWR value of higher than 1 seems to lower the risk of biliary complications after a live donor liver transplantation, these changes are not associated with the changes in total complication and acute rejection rates and patient survival. © 2023, Pamukkale University. All rights reserved.en_US
dc.identifier.doi10.31362/patd.1265140
dc.identifier.endpage419en_US
dc.identifier.issn1309-9833
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85169455402en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage412en_US
dc.identifier.trdizinid1193064en_US
dc.identifier.urihttps://doi.org/10.31362/patd.1265140
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1193064
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4393
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherPamukkale Universityen_US
dc.relation.ispartofPamukkale Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectGraft Recipient Weight Ratioen_US
dc.subjectLive Donoren_US
dc.subjectLiver Transplantationen_US
dc.titleUsing small size grafts in live donor liver transplantation: is size important?en_US
dc.typeArticleen_US

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