Cardiac biomarkers in the setting of asthma exacerbations: a review of clinical implications and practical considerations

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dc.authoridErtan Yetkin / 0000-0001-8862-750X
dc.authorscopusidErtan Yetkin / 7004009443
dc.authorwosidErtan Yetkin / AGX-3712-2022
dc.contributor.authorYalta, Kenan
dc.contributor.authorYalta, Tülin
dc.contributor.authorGürdoğan, Muhammet
dc.contributor.authorPalabıyık, Orkide
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2020-08-30T20:06:12Z
dc.date.available2020-08-30T20:06:12Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPalabiyik, Orkide/0000-0002-3488-3740en_US
dc.descriptionYetkin, Ertan (isu author)
dc.description.abstractPurpose of Review The present paper aims to highlight clinical implications of elevated cardiac biomarkers and associated myocardial dysfunction in a variety of cardiac and non-cardiac scenarios in patients with an asthma exacerbation, and to propose a basic algorithm for cardiovascular evaluation and triage (and hence, for further management) of these patients primarily based on evaluation of cardiac biomarkers along with basic diagnostic modalities and specific cardiac symptoms in the hospital setting. Recent Findings Elevation of cardiac biomarkers in the setting of an asthma exacerbation mostly signifies a new-onset subclinical myocardial dysfunction/injury generally associated with certain asthma-related factors including acute hypoxemia and bronchodilator therapy, and usually has a limited prognostic value in these patients. On the other hand, elevation of these biomarkers in patients with an asthma exacerbation might also denote a variety of certain life-threatening cardiac or non-cardiac conditions associated with significant myocardial dysfunction (acute coronary syndromes (ACSs), sepsis, etc.) that might be masked by the rampant course of the asthma exacerbation, and hence, might possibly go undetected potentially aggravating the prognosis in a portion of these patients. In patients with an asthma exacerbation, it seems imperative to timely diagnose and manage emerging diverse clinical conditions particularly through the guidance of cardiac biomarkers and associated myocardial dysfunction patterns in an effort to improve overall prognosis in these patients.en_US
dc.identifier.citationYalta, K., Yalta, T., Gurdogan, M., Palabιyιk, O., & Yetkιn, E. (2020). Cardiac Biomarkers in the Setting of Asthma Exacerbations: a Review of Clinical Implications and Practical Considerations. Pathology, 5, 6.en_US
dc.identifier.doi10.1007/s11882-020-00909-5en_US
dc.identifier.issn1529-7322en_US
dc.identifier.issn1534-6315en_US
dc.identifier.issue6en_US
dc.identifier.pmid32346818en_US
dc.identifier.scopus2-s2.0-85084169333en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s11882-020-00909-5
dc.identifier.urihttps://hdl.handle.net/20.500.12713/419
dc.identifier.volume20en_US
dc.identifier.wosWOS:000529340600001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYetkin, Ertanen_US
dc.language.isoenen_US
dc.publisherCurrent Medicine Groupen_US
dc.relation.ispartofCurrent Allergy and Asthma Reportsen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Biomarkersen_US
dc.subjectAsthmaen_US
dc.subjectAsthma Exacerbationen_US
dc.subjectTroponinsen_US
dc.subjectNatriuretic Peptidesen_US
dc.subjectN-Terminal Pro-Brain Natriuretic Peptide (Nt-Probnp)en_US
dc.subjectBrain Natriuretic Peptide (Bnp)en_US
dc.subjectClinical Implicationsen_US
dc.subjectMyocardial Dysfunctionen_US
dc.subjectPrognosisen_US
dc.titleCardiac biomarkers in the setting of asthma exacerbations: a review of clinical implications and practical considerationsen_US
dc.typeReview Articleen_US

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