Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism
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Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Oxford Univ Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Metastatic coloncancer has asurvival rate less than %5 despite the use of effective chemotherapeutic regimen. Prognosticand predictiveimportance of EGFR is still contradictivein coloncancer. Tyrosine kinase inhibitor canertinib was used in this study toblock the EGFR receptor. Theeffectof Palladium (Pd) (II)compound [PdCl(terpy)](sac).2H2O]andcanertinib combination treatment was investigated in this study. 5-fluorouracil(5-FU),a chemotherapeutic drug was used aspositive control.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Oncology
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
30
Sayı
Künye
Aydinlik, S., Uvez, A., Armutak, E. İ., Dere, E., & Ulukaya, E. (2019). 31P Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism. Annals of Oncology, 30(Supplement_5), mdz238-030.
