Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism

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dc.authoridEngin Ulukaya / 0000-0003-4875-5472en_US
dc.authorscopusidEngin Ulukaya / 6602927353
dc.authorwosidEngin Ulukaya / K-5792-2018
dc.contributor.authorAydınlık, S.
dc.contributor.authorÜvez, A.
dc.contributor.authorArmutak, E. I.
dc.contributor.authorDere, E.
dc.contributor.authorUlukaya, Engin
dc.date.accessioned2020-08-30T20:06:31Z
dc.date.available2020-08-30T20:06:31Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Metastatic coloncancer has asurvival rate less than %5 despite the use of effective chemotherapeutic regimen. Prognosticand predictiveimportance of EGFR is still contradictivein coloncancer. Tyrosine kinase inhibitor canertinib was used in this study toblock the EGFR receptor. Theeffectof Palladium (Pd) (II)compound [PdCl(terpy)](sac).2H2O]andcanertinib combination treatment was investigated in this study. 5-fluorouracil(5-FU),a chemotherapeutic drug was used aspositive control.en_US
dc.description.sponsorshipEuropean Soc Med Oncol, Japanese Soc Med Oncolen_US
dc.description.sponsorshipScientific Research Projects Foundation (BAP) of Uludag University of Turkeyen_US
dc.description.sponsorshipScientific Research Projects Foundation (BAP) of Uludag University of Turkey [Project No. (DDP(F)-2017)].en_US
dc.identifier.citationAydinlik, S., Uvez, A., Armutak, E. İ., Dere, E., & Ulukaya, E. (2019). 31P Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism. Annals of Oncology, 30(Supplement_5), mdz238-030.en_US
dc.identifier.issn0923-7534en_US
dc.identifier.issn1569-8041en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/545
dc.identifier.volume30en_US
dc.identifier.wosWOS:000491295500242en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorUlukaya, Enginen_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofAnnals of Oncologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleEffects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanismen_US
dc.typeConference Objecten_US

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