Fertility outcomes after preconceptional laparoscopic abdominal cerclage for second-trimester pregnancy losses

dc.authoridBengisu Küçükdemir / 0000-0003-4252-3830
dc.authorwosidBengisu Küçükdemir / FEJ-9962-2022
dc.contributor.authorDemirel, Cem
dc.contributor.authorGöksever Çelik, Hale
dc.contributor.authorTülek, Fırat
dc.contributor.authorKüçükdemir, Bengisu
dc.contributor.authorGökalp, Deniz
dc.contributor.authorErgin, Tolga
dc.contributor.authorLembet, Arda
dc.date.accessioned2020-12-30T07:53:39Z
dc.date.available2020-12-30T07:53:39Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective(s): Cervical incompetence is an important cause of recurrent pregnancy loss, typically presenting in the second trimester with silent cervical dilation and premature delivery of the fetus. We aimed to evaluate the conception rate and time to conception or failure to conceive after preconceptional laparoscopic abdominal cerclage (LAC). Study design: We conducted this retrospective observational cohort study at a tertiary referral center. Patients who underwent LAC in the nonpregnant state for a second-trimester pregnancy loss between June 2012 and February 2020 were included. Results: The subjects were 40 patients with a history of one or more second-trimester pregnancy losses despite the placement of vaginal cerclage, who had undergone LAC before contemplating a future pregnancy. The mean number of second-trimester pregnancy losses before LAC was two per woman. The ages of the women at the time of cerclage ranged from 21 to 42 years. The time to pregnancy, which was the primary outcome of the study, was determined as the number of menstrual cycles before the patient became pregnant after LAC and the number of cycles needed for the patient to achieve her latest pregnancy before LAC. Of the 40 women, 22.5 % were noted during the LAC operation to have a pelvic peritoneal pathology that might have affected fertility, and all such pathologies were treated concomitantly during the procedure. Spontaneous pregnancy rates before and after LAC were 96.4 % and 89.3 % (p = 0.299), and times to pregnancy before and after LAC were 6.3 ± 8.4 and 6.6 ± 8.1 cycles (p = 0.897). Neither difference was statistically significant. In more than 84 % of patients who became pregnant after LAC, pregnancy was sustained to the stage of viability.en_US
dc.identifier.citationDemirel, C., Celik, H. G., Tulek, F., Kucukdemir, B., Gokalp, D., Ergin, T., & Lembet, A. (2021). Fertility outcomes after preconceptional laparoscopic abdominal cerclage for second-trimester pregnancy losses. European Journal of Obstetrics & Gynecology and Reproductive Biology.en_US
dc.identifier.doi10.1016/j.ejogrb.2020.12.012en_US
dc.identifier.endpage63en_US
dc.identifier.issn0301-2115en_US
dc.identifier.issue10en_US
dc.identifier.pmid33360240en_US
dc.identifier.scopus2-s2.0-85098129089en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage59en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2020.12.012
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1296
dc.identifier.volume257en_US
dc.identifier.wosWOS:000609227800009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKüçükdemir, Bengisu
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology andReproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectServical Incompetenceen_US
dc.subjectConception Rateen_US
dc.subjectLaparoscopic Abdominal Cerclageen_US
dc.subjectSecond-trimester Pregnancy Lossen_US
dc.subjectTime to Conceptionen_US
dc.titleFertility outcomes after preconceptional laparoscopic abdominal cerclage for second-trimester pregnancy lossesen_US
dc.typeArticleen_US

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