Relationship between systemic immune-inflammation index and no-reflow in percutaneous coronary intervention for saphenous grafts

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dc.authoridSAHIN, ANIL/0000-0003-1956-2348
dc.authoridgurbak, ismail/0000-0001-8466-4354
dc.authorwosidSAHIN, ANIL/AFS-8068-2022
dc.authorwosidArslan, Enes/KFE-0586-2024
dc.authorwosidgurbak, ismail/HGA-8005-2022
dc.contributor.authorDemirci, Gokhan
dc.contributor.authorSahin, Ahmet A.
dc.contributor.authorAktemur, Tugba
dc.contributor.authorDemir, Ali R.
dc.contributor.authorCetin, Ilyas
dc.contributor.authorKarakurt, Huseyin
dc.contributor.authorArslan, Enes
dc.date.accessioned2024-05-19T14:38:49Z
dc.date.available2024-05-19T14:38:49Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective: In this study, we investigated the occurrence of no-reflow (NR) in percutaneous coronary intervention (PCI) for saphenous vein grafts (SVGs) and its relationship with a new systemic immune-inflammation index (SII) that determines inflammation. Methods: We studied 303 patients with acute coronary syndrome without ST elevation who underwent PCI for SVG disease. Results: NR formation during SVG PCI was significantly higher in patients with high SII (p < 0.001). NR occurrence was 12.8% when SII was & LE;548 and 41.9% when SII was >548. Conclusion: Our study is the first to investigate SII as the state of inflammation and its effect on the SVG PCI. Patients with higher SII have a higher risk of NR during an SVG for PCI. Plain language summaryThis study is about a type of surgery called bypass surgery, which is done to help when the heart is not working properly. During this surgery, doctors sometimes use veins in the leg to create new pathways for blood to flow around the heart. However, after a while these vessels can narrow or become blocked, so another procedure, stenting, is done to open them. Even after the stent is placed, the blood flow through the vein is sometimes not as good as it should be. This is called 'no reflow'. We wanted to investigate how often this problem occurs and whether it is related to a marker called the systemic immune-inflammation index (SII), which is a measure of inflammation in the body.We analyzed 303 patients who underwent stenting after a heart attack. We divided them into two groups according to their SII scores and investigated whether there was a difference in no-reflow occurrence between the two groups. We found that patients with a higher SII score were more likely to have no reflow during the stenting procedure, and an increased risk of no reflow if the SII score was above 548.This study was the first to look at SII and how it affects the stenting procedure for vessels used in bypass surgery.en_US
dc.identifier.doi10.2217/bmm-2023-0208
dc.identifier.endpage435en_US
dc.identifier.issn1752-0363
dc.identifier.issn1752-0371
dc.identifier.issue8en_US
dc.identifier.pmid37449860en_US
dc.identifier.scopus2-s2.0-85166394232en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage427en_US
dc.identifier.urihttps://doi.org10.2217/bmm-2023-0208
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4619
dc.identifier.volume17en_US
dc.identifier.wosWOS:001024959900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherFuture Medicine Ltden_US
dc.relation.ispartofBiomarkers In Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAcute Coronary Syndromeen_US
dc.subjectSiien_US
dc.subjectNo-Reflowen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectSaphenous Venous Graft Diseaseen_US
dc.titleRelationship between systemic immune-inflammation index and no-reflow in percutaneous coronary intervention for saphenous graftsen_US
dc.typeArticleen_US

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