Pediatric kidney care experience after the 2023 Türkiye earthquake

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dc.authoridSaygili, Seha Kamil/0000-0002-2424-6959
dc.authoridTurkkan, Ozde Nisa/0000-0003-2928-9031
dc.authoridözdemir atikel, yesim/0000-0001-5304-3125
dc.authoridYUKSEL, SELCUK/0000-0001-9415-1640
dc.authoridElhan, Atilla Halil/0000-0003-3324-248X
dc.authoridAksoy, Ozlem Yuksel/0000-0001-7905-3524
dc.authoridBAKKALOGLU EZGU, SEVCAN AZIME/0000-0001-6530-9672
dc.authorwosidSaygili, Seha Kamil/GLU-6742-2022
dc.authorwosidTurkkan, Ozde Nisa/HGV-0948-2022
dc.authorwosidözdemir atikel, yesim/GSI-4238-2022
dc.authorwosidYUKSEL, SELCUK/C-5473-2015
dc.authorwosidElhan, Atilla Halil/D-5519-2015
dc.contributor.authorBakkaloglu, Sevcan A.
dc.contributor.authorDelibas, Ali
dc.contributor.authorDoven, Serra Surmeli
dc.contributor.authorTaner, Sevgin
dc.contributor.authorYavuz, Sevgi
dc.contributor.authorErfidan, Gokcen
dc.contributor.authorVatansever, Esra Danaci
dc.date.accessioned2024-05-19T14:38:50Z
dc.date.available2024-05-19T14:38:50Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground. Two earthquakes on 6 February 2023 destroyed 10 cities in Turkiye. We report our experience with pediatric victims during these catastrophes, with a focus on crush syndrome related-acute kidney injury (Crush-AKI) and death. Method. Web-based software was prepared. Patient demographics, time under rubble (TUR), admission laboratory data, dialysis, and kidney and overall outcomes were recorded. Results. A total of 903 injured children (median age 11.62 years) were evaluated. Mean TUR was 13 h (interquartile range 32.5, max 240 h). Thirty-one of 32 patients with a TUR of >120 h survived. The patient who was rescued after 10 days survived. Two-thirds of the patients were given 50 mEq/L sodium bicarbonate in 0.45% sodium chloride solution on admission day. Fifty-eight percent of patients were given intravenous fluid (IVF) at a volume of 2000-3000 mL/m(2) body surface area (BSA), 40% at 3000-4000 mL/m(2) BSA and only 2% at >4000 mL/m(2) BSA. A total of 425 patients had surgeries, and 48 suffered from major bleeding. Amputations were recorded in 96 patients. Eighty-two and 66 patients required ventilator and inotropic support, respectively. Crush-AKI developed in 314 patients (36% of all patients). In all, 189 patients were dialyzed. Age >15 years, creatine phosphokinase (CK) >= 20 950 U/L, TUR >= 10 h and the first-day IVF volume <3000-4000 mL/m2 BSA were associated with Crush-AKI development. Twenty-two deaths were recorded, 20 of 22 occurring in patients with Crush-AKI and within the first 4 days of admission. All patients admitted after 7 days survived. Conclusions. These are the most extensive pediatric kidney disaster data obtained after an earthquake. Serum CK level was significantly associated with Crush-AKI at the levels of >20 950 U/L, but not with death. Adolescent age and initial IVF of less than 3000-4000 mL/m(2) BSA were also associated with Crush-AKI. Given that mildly injured victims can survive longer periods in the disaster field, we suggest uninterrupted rescue activity for at least 10 days.en_US
dc.identifier.doi10.1093/ndt/gfae033
dc.identifier.issn0931-0509
dc.identifier.issn1460-2385
dc.identifier.pmid38327222en_US
dc.identifier.urihttps://doi.org10.1093/ndt/gfae033
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4621
dc.identifier.wosWOS:001183242500001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofNephrology Dialysis Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectChildrenen_US
dc.subjectCrush Syndromeen_US
dc.subjectEarthquakeen_US
dc.subjectTurkiyeen_US
dc.titlePediatric kidney care experience after the 2023 Türkiye earthquakeen_US
dc.typeArticleen_US

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