Generation of induced pluripotent stem cells from human bone marrow-derived mesenchymal stem cells
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Link
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Adult somatic cells can be reprogrammed and become pluripotent called induced pluripotent stem cells (iPSC) when they are induced by the stemness genes. The iPSCs have been representing a research and development platform for cell-based therapies, and even in gene editing technologies as they provide the ability to differentiate almost all cell types. The efficiency of the protocols for the iPSC development defines the success of the experiments' outcome. Here, we describe the optimized protocol for obtaining human iPSCs derived from mesenchymal stem cells of bone-marrow origin to shed a light on the hurdles in the research laboratories.
Açıklama
Anahtar Kelimeler
Bone Marrow, Characterization, Induced Pluripotent Stem Cells, Mesenchymal Stem Cells, Transfection
Kaynak
Methods Mol Biol.
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
Sayı
Künye
Koyuncu Irmak, D., & Karaoz, E. (2021). Generation of Induced Pluripotent Stem Cells from Human Bone Marrow-Derived Mesenchymal Stem Cells. Methods in molecular biology (Clifton, N.J.), 10.1007/7651_2021_445. Advance online publication.
