Generation of induced pluripotent stem cells from human bone marrow-derived mesenchymal stem cells

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dc.authoridDuygu Koyuncu Irmak / 0000-0002-3277-5535en_US
dc.authoridErdal Karaöz / 0000-0002-9992-833Xen_US
dc.authorscopusidDuygu Koyuncu Irmak / 57219539042
dc.authorscopusidErdal Karaöz / 7003448087
dc.authorwosidErdal Karaöz / AAO-1470-2020
dc.contributor.authorKoyuncu Irmak, Duygu
dc.contributor.authorKaraöz, Erdal
dc.date.accessioned2021-11-11T10:11:12Z
dc.date.available2021-11-11T10:11:12Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractAdult somatic cells can be reprogrammed and become pluripotent called induced pluripotent stem cells (iPSC) when they are induced by the stemness genes. The iPSCs have been representing a research and development platform for cell-based therapies, and even in gene editing technologies as they provide the ability to differentiate almost all cell types. The efficiency of the protocols for the iPSC development defines the success of the experiments' outcome. Here, we describe the optimized protocol for obtaining human iPSCs derived from mesenchymal stem cells of bone-marrow origin to shed a light on the hurdles in the research laboratories.en_US
dc.identifier.citationKoyuncu Irmak, D., & Karaoz, E. (2021). Generation of Induced Pluripotent Stem Cells from Human Bone Marrow-Derived Mesenchymal Stem Cells. Methods in molecular biology (Clifton, N.J.), 10.1007/7651_2021_445. Advance online publication.en_US
dc.identifier.doi10.1007/7651_2021_445en_US
dc.identifier.pmid34724186en_US
dc.identifier.scopus2-s2.0-85132455751en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1007/7651_2021_445
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2224
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKoyuncu Irmak, Duygu
dc.institutionauthorKaraöz, Erdal
dc.language.isoenen_US
dc.publisherSpringer Linken_US
dc.relation.ispartofMethods Mol Biol.en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Marrowen_US
dc.subjectCharacterizationen_US
dc.subjectInduced Pluripotent Stem Cellsen_US
dc.subjectMesenchymal Stem Cellsen_US
dc.subjectTransfectionen_US
dc.titleGeneration of induced pluripotent stem cells from human bone marrow-derived mesenchymal stem cellsen_US
dc.typeArticleen_US

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