Combination therapy using nanomaterials and stem cells to treat spinal cord injuries

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dc.authoridAyça Bal Öztürk / 0000-0002-6502-528Xen_US
dc.authoridDuygu Koyuncu Irmak / 0000-0002-3277-5535en_US
dc.authoridAtefeh Zarepour / 0000-0002-0347-5840en_US
dc.authoridAli Zarrabi / 0000-0003-0391-1769en_US
dc.authorscopusidAyça Bal Öztürk / 57062000100
dc.authorscopusidDuygu Koyuncu Irmak / 57219539042
dc.authorscopusidAtefeh Zarepour / 56700291100
dc.authorscopusidAli Zarrabi / 23483174100
dc.authorwosidAyça Bal Öztürk / M-4472-2018en_US
dc.authorwosidAtefeh Zarepour / AAH-9225-2020en_US
dc.authorwosidAli Zarrabi / U-2602-2019en_US
dc.contributor.authorZarepour, Arezou
dc.contributor.authorBal Öztürk, Ayça
dc.contributor.authorKoyuncu Irmak, Duygu
dc.contributor.authorYaşayan, Gökçen
dc.contributor.authorGökmen, Aylin
dc.contributor.authorKaraöz, Erdal
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorZarrabi, Ali
dc.contributor.authorMostafavi, Ebrahim
dc.date.accessioned2022-07-21T07:15:51Z
dc.date.available2022-07-21T07:15:51Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.description.abstractAs a part of the central nervous system, the spinal cord (SC) provides most of the communications between the brain and other parts of the body. Any damage to SC interrupts this communication, leading to serious problems, which may remain for the rest of their life. Due to its significant impact on patients’ quality of life and its exorbitant medical costs, SC injury (SCI) is known as one of the most challengeable diseases in the world. Thus, it is critical to introduce highly translatable therapeutic platforms for SCI treatment. So far, different strategies have been introduced, among which utilizing various types of stem cells is one of the most interesting ones. The capability of stem cells to differentiate into several types of cell lines makes them promising candidates for the regeneration of injured tissues. One of the other interesting and novel strategies for SCI treatment is the appli- cation of nanomaterials, which could appear as a carrier for therapeutic agents or as a platform for culturing the cells. Combining these two approaches, stem cells and nanomaterials, could provide promising therapeutic strategies for SCI management. Accordingly, in this review we have summarized some of the recent advance- ments in which the applications of different types of stem cells and nanomaterials, alone and in combination forms, were evaluated for SCI treatment.en_US
dc.identifier.citationZarepour A, Bal Öztürk A, Koyuncu Irmak D, Yaşayan G, Gökmen A, Karaöz E, Zarepour A, Zarrabi A, Mostafavi E. Combination Therapy Using Nanomaterials and Stem Cells to Treat Spinal Cord Injuries. Eur J Pharm Biopharm. 2022 Jul 15:S0939-6411(22)00142-4. doi: 10.1016/j.ejpb.2022.07.004. Epub ahead of print. PMIDV.en_US
dc.identifier.doi10.1016/j.ejpb.2022.07.004en_US
dc.identifier.endpage240en_US
dc.identifier.issn0939-6411en_US
dc.identifier.pmid35850168en_US
dc.identifier.scopus2-s2.0-85134761814en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage224en_US
dc.identifier.urihttp://doi.org/10.1016/j.ejpb.2022.07.004
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3034
dc.identifier.volume177en_US
dc.identifier.wosWOS:000878845900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBal Öztürk, Ayça
dc.institutionauthorKoyuncu Irmak, Duygu
dc.institutionauthorZarepour, Atefeh
dc.institutionauthorZarrabi, Ali
dc.language.isoenen_US
dc.publisherElsevier Scienceen_US
dc.relation.ispartofEuropean Journal of Pharmaceutics and Biopharmaceuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectStem Cell Therapyen_US
dc.subjectNanomaterialsen_US
dc.subjectNeuronen_US
dc.subjectRegenerative Medicineen_US
dc.subjectSpinal Cord Injuryen_US
dc.titleCombination therapy using nanomaterials and stem cells to treat spinal cord injuriesen_US
dc.typeArticleen_US

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