Ionizing radiation exposure due to medical imaging in hematopoietic stem cell transplant recipients
Yükleniyor...
Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ISTANBUL TRAINING & RESEARCH HOSPITAL
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: The study aimed to quantify the ionizing radiation exposure of patients with hematologic malignancy who underwent hematopoietic stem cell transplantation (HSCT). Methods: This was a retrospective evaluation of the adult patients who underwent allogeneic or autologous HSCT for hematologic malignities in a single center between January 2016 and September 2020. All radiological imaging procedures involving ionizing radiation screened study participants. The study period covered both the pre- and post-transplantation phases. A typical cumulative effective dose (CED) was used to calculate the exposed ionizing radiation in units of millisieverts (mSv). Results: A total of 120 patients (females 38.3%, mean age: 52.2 +/- 15.6 years) were included. Autologous HSCT was performed in 66 patients (55%), whereas 54 patients (45%) underwent allogeneic HSCT. Patients with acute myeloid leukemia and acute lymphoblastic leukemia comprised 53.7% and 31.5% of allogeneic HSCT, respectively. Autologous HSCT was mainly performed in patients with multiple myeloma (47%) and non-hodgkin lymphoma (34.8%). The median total CED was 11.85 mSv (interquartile range: 4.08-19.78). The median CED of allogeneic HSCT patients was significantly higher than that of the autologous HSCT group. The vast majority of the total CED (92.3%) comes from computed tomography imaging procedures. In the entire groups, 92 patients (76.7%) received a low dose (<20 mSv), whereas 26 patients (21.7%) received a moderate dose (>20-50 mSv) ionizing radiation. Conclusion: One-third of all HSCT patients received a moderate ionizing radiation dose. Allogeneic HSCT patients had significantly higher median CED than autologous counterparts.
Açıklama
Anahtar Kelimeler
Computed Tomography, Cumulative Effective Dose, Ionizing Radiation, Radiation Exposure, Hematopoietic Stem Cell Transplantation
Kaynak
ISTANBUL MEDICAL JOURNAL
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
23
Sayı
2
