COVID-19: booster(s) vs. hospitalization and Intensive Care Unit admission

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dc.authoridKetencioğlu, Burcu Baran/0000-0002-6757-3140
dc.authoridKızılırmak, Deniz/0000-0001-9445-1598
dc.authoridBerik Safçi, Sinem/0000-0002-0977-0015
dc.authoridTure, Zeynep/0000-0001-6895-0318
dc.authoridAkkaya Isik, Sinem/0000-0001-9941-2993
dc.authoridEREN KUTSOYLU, OYA/0000-0003-3814-0474
dc.authoridBAYDAR TOPRAK, OYA/0000-0001-7320-976X
dc.authorwosidKetencioğlu, Burcu Baran/AAO-9889-2021
dc.authorwosidArgun Baris, Serap/JLL-6114-2023
dc.authorwosidEser, Fatma/AAO-3498-2021
dc.authorwosidKızılırmak, Deniz/HJH-3124-2023
dc.authorwosidBerik Safçi, Sinem/HDO-1349-2022
dc.authorwosidTure, Zeynep/AGF-0133-2022
dc.authorwosidAkkaya Isik, Sinem/JLM-2026-2023
dc.contributor.authorToprak, O. Baydar
dc.contributor.authorAkpolat, T.
dc.contributor.authorUzun, O.
dc.contributor.authorDeniz, P. Pinar
dc.contributor.authorKokturk, N.
dc.contributor.authorVarol, A.
dc.contributor.authorGuzel, E.
dc.date.accessioned2024-05-19T14:40:30Z
dc.date.available2024-05-19T14:40:30Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractOBJECTIVE: As the pandem-ic continues, different vaccine protocols have been implemented to maintain the protection of vaccines and to provide protection against new variants. The aim of this study was to as-sess hospitalized patients' vaccination status and document the efficacy of boosters.PATIENTS AND METHODS: The patients that were hospitalized due to COVID-19 were enrolled from 28 hospitals in Turkey for five months from September 2021. 5,331 confirmed COVID-19 pa-tients from collaborating centers were random-ly enrolled to understand/estimate the distri-bution of vaccination status in hospitalized pa-tients and to compare the efficacy of vaccina-tion/booster protocols.RESULTS: 2,779 men and 2,552 women of which 2,408 (45.2%) were admitted to Intensive Care Units participated in this study. It was found that the highest risk reduction for all age groups was found in groups that received 4 doses. Four doses of vaccination for every 3.7 people under 50 years of age, for every 5.7 people in the 50-64 age group, and for every 4.3 people over 65 years of age will prevent 1 patient from being admitted to intensive care. Regardless of the type of vaccine, it was found that the risk of ICU hospitalization decreased in those who were vaccinated compared to those who were not vaccinated. Regardless of the type of vaccine, the ICU risk was found to decrease 1.25-fold in those who received 1 or 2 doses of vaccine, 1.18-fold in those who received 3 dos-es, and 3.26-fold in those who received 4 doses.CONCLUSIONS: The results suggested that the addition of a fourth dose is more effective in preventing intensive unit care even in disad-vantaged.en_US
dc.description.sponsorshipTurkish Thoracic Societyen_US
dc.description.sponsorshipThe authors want to thank Turkish Thoracic Society for funding this study.en_US
dc.identifier.endpage2142en_US
dc.identifier.issn1128-3602
dc.identifier.issue5en_US
dc.identifier.pmid36930513en_US
dc.identifier.scopus2-s2.0-85150666602en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2132en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4971
dc.identifier.volume27en_US
dc.identifier.wosWOS:000960863600014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCovid-19en_US
dc.subjectBoosteren_US
dc.subjectVaccinationen_US
dc.subjectHospitalizationen_US
dc.subjectVaccine Effectivenessen_US
dc.titleCOVID-19: booster(s) vs. hospitalization and Intensive Care Unit admissionen_US
dc.typeArticleen_US

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