Effect of osteosarcopenia on the development of a second compression fracture and mortality in elderly patients after vertebroplasty

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dc.contributor.authorKara, Gokhan Kursat
dc.contributor.authorOzturk, Cagatay
dc.date.accessioned2024-05-19T14:40:20Z
dc.date.available2024-05-19T14:40:20Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractObjective: This study aimed to investigate the effect of osteosarcopenia on second fracture development and mortality in patients aged above 60 years undergoing vertebroplasty because of osteoporotic vertebral compression fracture (OVCF).Methods: A retrospective evaluation was conducted on 104 patients treated by vertebroplasty because of OVF between 2016 and 2021. The L3 vertebra Hounsfield unit values and the psoas muscle index (PMI) values measured at the L3 vertebra level were obtained from the patients' medical data and computed tomography images. Using these measurements, the patients were divided into 3 groups: only osteoporosis (OO group), only sarcopenia (OS group), and osteosarcopenia (OSP group). Differences between the groups were evaluated regarding second OVCF development and mortality. Results: The study included 104 patients, comprising 30 males and 74 females aged 60-92 years. The OS group included 10 patients, the OO group included 54 patients, and the OSP group consisted of 40 patients. A single vertebral fracture occurred in 72 patients, and 2 vertebral fractures occurred in 32 patients. The chi-square test, Mann-Whitney U-test, Kruskal-Wallis test, and Kaplan-Meier survival analysis results showed no statistically significant difference between the 3 groups for the risk of second vertebral fracture. Sarcopenia, either alone or in combination with osteoporosis, was seen to have a negative effect on the survival of patients who underwent vertebro-plasty following a vertebral fracture.Conclusion: This study has shown that osteosarcopenia did not increase the risk of developing a second vertebral fracture, but it increased mortality 2.8-fold for those who underwent vertebroplasty after vertebral fracture.en_US
dc.identifier.doi10.5152/j.aott.2023.23099
dc.identifier.issn1017-995X
dc.identifier.issn2589-1294
dc.identifier.issue5en_US
dc.identifier.pmid37909684en_US
dc.identifier.scopus2-s2.0-85175351580en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org10.5152/j.aott.2023.23099
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4945
dc.identifier.volume57en_US
dc.identifier.wosWOS:001127628500010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Orthopaedics Traumatologyen_US
dc.relation.ispartofActa Orthopaedica Et Traumatologica Turcicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCompression Fractureen_US
dc.subjectOsteoporosisen_US
dc.subjectSarcopeniaen_US
dc.subjectOsteosarcopeniaen_US
dc.titleEffect of osteosarcopenia on the development of a second compression fracture and mortality in elderly patients after vertebroplastyen_US
dc.typeArticleen_US

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