Wharton's jelly-derived mesenchymal stem cell transplantation in a patient with hypoxic-ischemic encephalopathy: a pilot study

Basit Öğe Kaydı
dc.authoridErdal Karaöz / 0000-0002-9992-833Xen_US
dc.authorscopusidErdal Karaöz / 7003448087
dc.authorwosidErdal Karaöz / IXE-6677-2023
dc.contributor.authorKabataş, Serdar
dc.contributor.authorCivelek, Erdinç
dc.contributor.authorİnci, Çiğdem
dc.contributor.authorYalçınkaya, Ebru Yılmaz
dc.contributor.authorGünel, Gülşen
dc.contributor.authorKır, Gülay
dc.contributor.authorAlbayrak, Esra
dc.contributor.authorÖztürk, Erek
dc.contributor.authorAdaş, Gökhan
dc.contributor.authorKaraöz, Erdal
dc.date.accessioned2020-08-30T20:07:19Z
dc.date.available2020-08-30T20:07:19Z
dc.date.issued2018
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000446855200002en_US
dc.description.abstractWharton's jelly-derived mesenchymal stem cells (WJ-MSCs) have been introduced as a possible therapy in hypoxic-ischemic encephalopathy (HIE). We report a 16-year-old boy who was treated with WJ-MSCs in the course of HIE due to post-cardiopulmonary resuscitation. He received a long period of mechanical ventilation and tracheostomy with spastic quadriparesis. He underwent the intrathecal (1x10(6)/kg in 3 mL), intramuscular (1x10(6)/kg in 20 mL) and intravenous (1x10(6)/kg in 30 mL) administrations of WJ-MSCs for each application route (twice a month for 2 months). After stem cell infusions, progressive improvements were shown in his neurological examination, neuroradiological, and neurophysiological findings. To our best knowledge, this is a pioneer project to clinically study the neural repair effect of WJ-MSCs in a patient with HIE.en_US
dc.identifier.citationKabatas, S., Civelek, E., Inci, C., Yalcinkaya, E. Y., Gunel, G., Kir, G., … Karaoz, E. (2018). Wharton’s Jelly-Derived Mesenchymal Stem Cell Transplantation in a Patient with Hypoxic-Ischemic Encephalopathy: A Pilot Study. CELL TRANSPLANTATION, 27(10), 1425–1433. https://doi.org/10.1177/0963689718786692en_US
dc.identifier.doi10.1177/0963689718786692en_US
dc.identifier.endpage1433en_US
dc.identifier.issn0963-6897en_US
dc.identifier.issn1555-3892en_US
dc.identifier.issue10en_US
dc.identifier.pmid30203688en_US
dc.identifier.scopus2-s2.0-85054634600en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1425en_US
dc.identifier.urihttps://doi.org/10.1177/0963689718786692
dc.identifier.urihttps://hdl.handle.net/20.500.12713/741
dc.identifier.volume27en_US
dc.identifier.wosWOS:000446855200002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaraöz, Erdalen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofCell Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypoxic-Ischemic Encephalopathyen_US
dc.subjectPost-Cardiopulmonary Resuscitationen_US
dc.subjectStem Cell Therapyen_US
dc.subjectWharton's Jellyen_US
dc.titleWharton's jelly-derived mesenchymal stem cell transplantation in a patient with hypoxic-ischemic encephalopathy: a pilot studyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
h141.pdf
Boyut:
532.01 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Makale Koleksiyonu