Application of Convergent Science and Technology toward Ocular Disease Treatment

Basit Öğe Kaydı
dc.authoridÖZCAN BÜLBÜL, Ece/0000-0001-7112-923X
dc.authoridCecen, Berivan/0000-0002-0081-2004
dc.authoridZarrabi, Ali/0000-0003-0391-1769
dc.authoridZarepour, Atefeh/0000-0002-0347-5840
dc.authoridGÜLTEKİN, HAZAL EZGİ/0000-0001-6438-8006
dc.authoridCetinel, Sibel/0000-0003-0248-9447
dc.authoridBAL OZTURK, AYCA/0000-0002-6502-528X
dc.authorwosidÖZCAN BÜLBÜL, Ece/ACE-7724-2022
dc.authorwosidCecen, Berivan/Q-4203-2019
dc.authorwosidZarrabi, Ali/U-2602-2019
dc.authorwosidZarepour, Atefeh/AAH-9225-2020
dc.authorwosidGÜLTEKİN, HAZAL EZGİ/JTU-8870-2023
dc.authorwosidBAL OZTURK, AYCA/M-4472-2018
dc.contributor.authorBal-Ozturk, Ayca
dc.contributor.authorOzcan-Bulbul, Ece
dc.contributor.authorGultekin, Hazal Ezgi
dc.contributor.authorCecen, Berivan
dc.contributor.authorDemir, Ebru
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorCetinel, Sibel
dc.date.accessioned2024-05-19T14:46:05Z
dc.date.available2024-05-19T14:46:05Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractEyes are one of the main critical organs of the body that provide our brain with the most information about the surrounding environment. Disturbance in the activity of this informational organ, resulting from different ocular diseases, could affect the quality of life, so finding appropriate methods for treating ocular disease has attracted lots of attention. This is especially due to the ineffectiveness of the conventional therapeutic method to deliver drugs into the interior parts of the eye, and the also presence of barriers such as tear film, blood-ocular, and blood-retina barriers. Recently, some novel techniques, such as different types of contact lenses, micro and nanoneedles and in situ gels, have been introduced which can overcome the previously mentioned barriers. These novel techniques could enhance the bioavailability of therapeutic components inside the eyes, deliver them to the posterior side of the eyes, release them in a controlled manner, and reduce the side effects of previous methods (such as eye drops). Accordingly, this review paper aims to summarize some of the evidence on the effectiveness of these new techniques for treating ocular disease, their preclinical and clinical progression, current limitations, and future perspectives.en_US
dc.identifier.doi10.3390/ph16030445
dc.identifier.issn1424-8247
dc.identifier.issue3en_US
dc.identifier.pmid36986546en_US
dc.identifier.scopus2-s2.0-85151763225en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.3390/ph16030445
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5436
dc.identifier.volume16en_US
dc.identifier.wosWOS:000958721600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofPharmaceuticalsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectOcular Diseaseen_US
dc.subjectSmart Contact Lensen_US
dc.subjectNanotechnologyen_US
dc.subjectDrug Deliveryen_US
dc.subjectConvergent Scienceen_US
dc.titleApplication of Convergent Science and Technology toward Ocular Disease Treatmenten_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu