Effect of Puberty, Menstruation, Pregnancy, Lactation, and Menopause on Chronic Urticaria Activity

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dc.authoridTerzi, Özlem/0000-0002-9524-5582
dc.authoridOrnek, Sinem Ayse/0000-0002-1536-6035
dc.authoridKocaturk, Emek/0000-0003-2801-0959
dc.authorwosidTerzi, Özlem/D-7697-2016
dc.authorwosidOrnek, Sinem Ayse/ABF-1555-2021
dc.authorwosidKocaturk, Emek/ABD-8447-2020
dc.contributor.authorOrnek, Sinem Ayse
dc.contributor.authorSuroji Alkilinc, Alisa
dc.contributor.authorKiziltac, Utkan
dc.contributor.authorKiziltac, Kubra
dc.contributor.authorKocaturk, Emek
dc.date.accessioned2024-05-19T14:45:47Z
dc.date.available2024-05-19T14:45:47Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground: Chronic urticaria (CU) is a systemic disorder which is characterized by recurrent wheals and/or angioedema lasting more than 6 weeks. Sex hormones have been suggested to play a role in CU pathogenesis, however, their clinical implications have not been adequately described in the literature. Objective: To determine whether conditions that change sex hormone levels such as puberty, menstruation, pregnancy, breastfeeding, and menopause affect the course of CU. Methods: This cross-sectional questionnaire study was conducted on female CU patients at Okmeydani Training and Research Hospital UCARE Center between 2016 and 2017. The open-ended questionnaire consisted of questions evaluating the effects of hormonal changes on disease course. Results: A total of 111 female CU patients were included in the analysis. During the perimenstrual period, CU symptoms worsened in 29% of patients but improved in 4.8%. The disease course did not change in the majority of patients during puberty, pregnancy, lactation, or menopause (100%, 96%, 83.8%, and 95.6%, respectively). Conclusions: Contrary to expectations, a change in sex hormone levels had no effect on the course of CU in the majority of cases. However, disease activity increased in one-third of CU patients during the perimenstrual period.en_US
dc.identifier.doi10.1177/12034754231191472
dc.identifier.endpage471en_US
dc.identifier.issn1203-4754
dc.identifier.issn1615-7109
dc.identifier.issue5en_US
dc.identifier.pmid37537974en_US
dc.identifier.scopus2-s2.0-85166979292en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage466en_US
dc.identifier.urihttps://doi.org10.1177/12034754231191472
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5347
dc.identifier.volume27en_US
dc.identifier.wosWOS:001042380300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal of Cutaneous Medicine and Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectMenopauseen_US
dc.subjectMenstruationen_US
dc.subjectPregnancyen_US
dc.subjectSex Hormonesen_US
dc.subjectUrticariaen_US
dc.titleEffect of Puberty, Menstruation, Pregnancy, Lactation, and Menopause on Chronic Urticaria Activityen_US
dc.typeArticleen_US

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