The relationship between ultrasonographically measured testicular volumes and cord blood inhibin B concentrations in healthy term male neonates

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dc.authoridCanda, Ebru/0000-0002-9175-1998
dc.authorwosidCanda, Ebru/JXX-2666-2024
dc.contributor.authorErsoy, Betuel
dc.contributor.authorOvali, Guelguen Yilmaz
dc.contributor.authorCanda, Ebru
dc.contributor.authorOnur, Ece
dc.contributor.authorOzyurt, Beyhan Cengiz
dc.contributor.authorTansug, Nermin
dc.date.accessioned2024-05-19T14:45:59Z
dc.date.available2024-05-19T14:45:59Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractSerum inhibin B (INHB) concentrations are associated with testicular volumes (TV) in all periods of childhood. The aim of the study was to investigate the relationship between TV measured by ultrasonography (US) and cord blood inhibin B and total testosterone (TT) concentrations, stratified by mode of delivery. In total 90 male infants were included. Testes of healthy, term newborns were evaluated by US on the third day after delivery. TV were calculated using two formulae: The ellipsoid formula [length (mm) x width (mm2) x & pi;/6] and Lambert formula [length (mm) x width (mm) x height (mm) x 0.71]. Cord blood was taken for the determination of total testosterone (TT) and INHB. TT and INHB concentrations were evaluated according to TV percentiles (<10th, 10th-90th, >90th). There was a strong positive correlation between mean TV calculated with both formulae by percentile group (r = 0.777, r = 0.804, r = 0.846; p < 0.001). Cord blood INHB, but not TT were significantly lower in newborns with TV < 10th percentile compared to those with TV between 10 and 90th percentile and > 90th percentile (p < 0.05). There was a positive correlation between left and right TV calculated by either formula, and cord blood INHB (r = 0.212, 0.313, 0.320, 0.246, p < 0.05), not TT. There was no significant difference between hormones and TV when grouped by mode of delivery (p > 0.05). The Lambert and ellipsoid formulas are equally reliable in calculating neonatal testicular by ultrasound. INHB concentration is high in cord blood and positively correlated with neonatal TV. Cord blood INHB concentration may be an indicator for early detection of testicular structure and function disorders in neonates.en_US
dc.identifier.doi10.1016/j.repbio.2023.100786
dc.identifier.issn1642-431X
dc.identifier.issn2300-732X
dc.identifier.issue3en_US
dc.identifier.pmid37429065en_US
dc.identifier.scopus2-s2.0-85164444552en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org10.1016/j.repbio.2023.100786
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5411
dc.identifier.volume23en_US
dc.identifier.wosWOS:001039669400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofReproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectNeonateen_US
dc.subjectTesticular Volumeen_US
dc.subjectCord Blooden_US
dc.subjectInhibin Ben_US
dc.subjectUltrasonographyen_US
dc.titleThe relationship between ultrasonographically measured testicular volumes and cord blood inhibin B concentrations in healthy term male neonatesen_US
dc.typeArticleen_US

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