Development of lateral flow assays for rapid detection of troponin ı: a review

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dc.authoridAli Zarrabi / 0000-0003-0391-1769en_US
dc.authorscopusidAli Zarrabi / 23483174100en_US
dc.authorwosidAli Zarrabi / U-2602-2019en_US
dc.contributor.authorMohammadinejad, Arash
dc.contributor.authorNooranian, Samin
dc.contributor.authorOskuee, Reza Kazemi
dc.contributor.authorMirzaei, Sepideh
dc.contributor.authorAleyaghoob, Ghazaleh
dc.contributor.authorZarrabi, Ali
dc.date.accessioned2022-12-12T05:37:39Z
dc.date.available2022-12-12T05:37:39Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.description.abstractTroponin I as a particular and major biomarker of cardiac failure is released to blood demonstrating hurt of myocardial cells. Unfortunately, troponin I detection in the first hours of acute myocardial infarction usually faces with most negligence. Therefore, developments of point of care devices such as lateral flow strips are highly required for timely diagnosis and prognosis. Lateral flow assays are low-cost paper-based detection platforms relying on specific diagnostic agents such as aptamers and antibodies for a rapid, selective, quantitative and semi-quantitative detection of the analyte in a complex mixture. Moreover, lateral flow assay devices are portable, and their simplicity of use eliminates the need for experts or any complicated equipment to operate and interpret the test results. Additionally, by coupling the lateral flow assay technology with nanotechnology, for labeling and signal amplification, many breakthroughs in the field of diagnostics have been achieved. The present study reviews the use of lateral flow assays in early stage, quantitative, and sensitive detection of cardiac troponin I and mainly focuses on the structure of each type of developed lateral flow assays. Finally, this review summarized the improvements, detection time, and limit of detection of each study as well as the advantages and disadvantages.en_US
dc.identifier.citationMohammadinejad, A., Nooranian, S., Kazemi Oskuee, R., Mirzaei, S., Aleyaghoob, G., Zarrabi, A., ... & Sheikh Beig Goharrizi, M. A. (2022). Development of Lateral Flow Assays for Rapid Detection of Troponin I: A Review. Critical Reviews in Analytical Chemistry, 1-15.en_US
dc.identifier.doi10.1080/10408347.2022.2144995en_US
dc.identifier.issn1040-8347en_US
dc.identifier.issn1547-6510en_US
dc.identifier.scopus2-s2.0-85142230234en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttp://dx.doi.org/10.1080/10408347.2022.2144995
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3462
dc.identifier.wosWOS:000884237500001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorZarrabi, Ali
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofCRITICAL REVIEWS IN ANALYTICAL CHEMISTRYen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiac Failuresen_US
dc.subjectLateral Flowassayen_US
dc.subjectTroponinen_US
dc.titleDevelopment of lateral flow assays for rapid detection of troponin ı: a reviewen_US
dc.typeReview Articleen_US

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