Assessment of the vitamin D status and its determinants in young healthy students from Palestine

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dc.authoridSchuchardt, Jan Philipp/0000-0003-1724-6325
dc.contributor.authorLenz, Janina Susann
dc.contributor.authorTintle, Nathan
dc.contributor.authorKerlikowsky, Felix
dc.contributor.authorBadrasawi, Manal
dc.contributor.authorZahdeh, Rana
dc.contributor.authorQasrawi, Radwan
dc.contributor.authorHahn, Andreas
dc.date.accessioned2024-05-19T14:39:45Z
dc.date.available2024-05-19T14:39:45Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractThe global prevalence of vitamin D deficiency is high. Poor vitamin D status, especially in women, has been reported in several countries in the Middle East despite adequate year-round sunlight for vitamin D synthesis. However, data on vitamin D status in Palestine are scarce. The aim of this cross-sectional study was to evaluate vitamin D status based on serum concentrations of 25-hydroxycholecalciferol [25-(OH)D] among young healthy Palestinian students (18-27 years) and to assess associations between 25-(OH)D concentrations and several predictors. The mean 25-(OH)D concentration of women (n 151) was 27.2 +/- 14.5 nmol/l, with the majority having insufficient (31.1 %) or deficient (<60 %) 25-(OH)D status. Only 7 % of women achieved sufficient or optimal 25-(OH)D status. In contrast, men (n 52) had a mean 25-(OH)D concentration of 58.3 +/- 14.5 nmol/l, with none classified as deficient, and most obtaining sufficient (55.8 %) or even optimal 25-(OH)D status (11.5 %). Among women, 98 % wore a hijab and 74 % regularly used sunscreen. Daily dietary vitamin D intake (3-d 24-h recalls) was 45.1 +/- 36.1 IU in the total group (no sex differences). After adjustment, multiple linear regression models showed significant associations between 25-(OH)D concentrations and the use of supplements (B = 0.069; P = 0.020) and dietary vitamin D (B = 0.001; P = 0.028). In gender-stratified analysis, the association between supplement use and 25-(OH)D concentrations was significant in women (B = 0.076; P = 0.040). The vitamin D status of women in the present cohort is critical and appears to be mainly due to wearing a hijab, regular use of sunscreen and low dietary vitamin D intake. The vitamin D status of the women should be improved by taking vitamin D containing supplements or fortified foods.en_US
dc.description.sponsorshipBundesministerium fur Bildung und Forschung (BMBF) [FKZ: 01DH19003]en_US
dc.description.sponsorshipThis work was partly supported by grants from the Bundesministerium fur Bildung und Forschung (BMBF, FKZ: 01DH19003) to A. H. and J. P. S.en_US
dc.identifier.doi10.1017/jns.2023.25
dc.identifier.issn2048-6790
dc.identifier.pmid38415242en_US
dc.identifier.scopus2-s2.0-85150351397en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.1017/jns.2023.25
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4842
dc.identifier.volume12en_US
dc.identifier.wosWOS:000949280700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofJournal of Nutritional Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCalcidiolen_US
dc.subjectMiddle Easten_US
dc.subjectVitamin D Deficiencyen_US
dc.subjectVitamin D Status Predictorsen_US
dc.titleAssessment of the vitamin D status and its determinants in young healthy students from Palestineen_US
dc.typeArticleen_US

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