Malignancy in patients with sarcoidosis

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dc.authoridŞenol Kobak / 0000-0001-8270-640Xen_US
dc.authorscopusidŞenol Kobak / 12782228700
dc.authorwosidŞenol Kobak / 12782228700
dc.contributor.authorKobak, Şenol
dc.contributor.authorYıldız, Fidan
dc.contributor.authorSemiz, Hüseyin
dc.contributor.authorOrman Mehmet Akif
dc.date.accessioned2020-08-30T20:01:37Z
dc.date.available2020-08-30T20:01:37Z
dc.date.issued2021
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed Yılı: 2019
dc.description.abstractThe relationship between sarcoidosis and malignancy is not clear yet. We retrospectively evaluated 131 sarcoidosis patients followed-up at the single Rheumatology center. The incidence of malignancies was investigated in this cohort. A total of 6 (4.6%) patients with malignancy were identified in our cohort of 131 patients with sarcoidosis. Hodgkin lymphoma (HL) was detected in three patients, followed by one patient with breast cancer, one patient with thyroid cancer and one patient with testicular cancer. All patients had chronic sarcoidosis with pulmonary involvement, and only 1 patient had acute sarcoidosis with Löfgren's syndrome. HL developed concomitantly with sarcoidosis in one patient while other two patients developed disease before and after sarcoidosis diagnosis. Two patients with solid tumors developed malignancy years before sarcoidosis diagnosis, while one patient developed thyroid cancer during sarcoidosis follow-up. All 6 sarcoidosis–malignancy patients survived after six year years follow up. We found low incidence of malignancy in patients with sarcoidosis in our small cohort. The sarcoidosis–malignancy relationship can only be a coincidence and/or can be explained by a common pathogenesis. New prospective studies involving large patients series are needed in this regard. © 2019 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatologíaen_US
dc.identifier.citationKobak, S., Yildiz, F., Semiz, H., & Orman, M. (2019). Malignancy in patients with sarcoidosis. Reumatología Clínica.en_US
dc.identifier.doi10.1016/j.reuma.2019.04.003en_US
dc.identifier.issn1699258Xen_US
dc.identifier.pmid31153889en_US
dc.identifier.scopus2-s2.0-85066129328en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1016/j.reuma.2019.04.003
dc.identifier.urihttps://hdl.handle.net/20.500.12713/322
dc.identifier.wosWOS:000608393600010en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKobak, Şenolen_US
dc.language.isoenen_US
dc.publisherEdiciones Doyma, S.L.en_US
dc.relation.ispartofReumatologia Clinicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIncidenceen_US
dc.subjectMalignancyen_US
dc.subjectSarcoidosisen_US
dc.titleMalignancy in patients with sarcoidosisen_US
dc.title.alternativeMalignidad en pacientes con sarcoidosisen_US
dc.typeArticleen_US

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