Isolation, culture, cryopreservation, and preparation of umbilical cord-derived mesenchymal stem cells as a final cellular product under good manufacturing practices-compliant conditions

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Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Mesenchymal stem cells have gained popularity in cell-based therapies due to their regenerative capabilities, immunomodulation properties, and paracrine activity through trophic factors. It is of utmost importance to establish clinical-grade procedures for the preparation of the mesenchymal stem cells for clinical applications. Here, we describe detailed procedures for isolation, culture, cryopreservation, and preparation of mesenchymal stem cells derived from umbilical cord as a final product under good manufacturing practices-compliant conditions.

Açıklama

Anahtar Kelimeler

Cell Isolation, Cell Therapy, Culture, GMP, Stem Cells, Umbilical Cord

Kaynak

Methods in molecular biology

WoS Q Değeri

N/A

Scopus Q Değeri

N/A

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Sayı

Künye

Aydoğdu, N., Öztel, O. N., & Karaöz, E. (2020). Isolation, Culture, Cryopreservation, and Preparation of Umbilical Cord-Derived Mesenchymal Stem Cells as a Final Cellular Product Under Good Manufacturing Practices-Compliant Conditions. Methods in molecular biology (Clifton, N.J.), 10.1007/7651_2020_332. Advance online publication. https://doi.org/10.1007/7651_2020_332