Elderly - onset sarcoidosis: a single center comparative study

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dc.authoridŞenol Kobak / 0000-0001-8270-640X
dc.authorscopusidŞenol Kobak / 12782228700
dc.authorwosidŞenol Kobak / AAO-2482-2020
dc.contributor.authorKobak, Şenol
dc.contributor.authorYıldız, Fidan
dc.contributor.authorSemiz, Hüseyin
dc.contributor.authorOrman, Mehmet Akif
dc.date.accessioned2020-08-30T20:01:33Z
dc.date.available2020-08-30T20:01:33Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjectives: Sarcoidosis rarely affect patients older than 65 years old. The purpose of this study is to compare and evaluate the demographic, clinical and laboratory features of elderly-onset (EOS) and young-onset sarcoidosis (YOS) patients. Methods: One hundred and thirty one patients diagnosed with sarcoidosis according to clinical, radiologic and histopathological evaluation were included in this study. The patients with initial symptoms started after age 65 were accepted as EOS. Results: Twenty (15.3%) of 131 patients were diagnosed as EOS, and 111 (84.7%) patients were evaluated as YOS. Fifteen of 20 EOS patients were female and 5 of them were male. Average duration of the disease was determined as 38.4 months for YOS and 22.5 months for EOS (p = 0.556). Delay of the diagnosis was 12 months for YOS while it was 3 months for EOS (p = 0.001). Higher rates of fatique, comorbid diseases and more hydroxychloroquine (HQ) use were detected in EOS patients comparing to YOS (p = 0.010, p = 0.003 and p = 0.039 respectively). Conclusions: EOS patients are characterized with higher rates of fatique and comorbid diseases, less inflammatory sign and delayed diagnosis, and less DMARDs use. © 2018 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatologíaen_US
dc.identifier.citationKobak, S., Yildiz, F., Semiz, H., & Orman, M. (2020). Elderly-onset sarcoidosis: a single center comparative study. Reumatología Clínica (English Edition), 16(3), 235-238.en_US
dc.identifier.doi10.1016/j.reuma.2018.06.004en_US
dc.identifier.endpage238en_US
dc.identifier.issn1699258Xen_US
dc.identifier.issue3en_US
dc.identifier.pmid30054252en_US
dc.identifier.scopus2-s2.0-85050283887en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage235en_US
dc.identifier.urihttps://doi.org/10.1016/j.reuma.2018.06.004
dc.identifier.urihttps://hdl.handle.net/20.500.12713/285
dc.identifier.volume16en_US
dc.identifier.wosWOS:000575369900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKobak, Şenolen_US
dc.language.isoenen_US
dc.publisherEdiciones Doyma, S.L.en_US
dc.relation.ispartofReumatologia Clinicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElderly-Onseten_US
dc.subjectFeaturesen_US
dc.subjectSarcoidosisen_US
dc.titleElderly - onset sarcoidosis: a single center comparative studyen_US
dc.typeArticleen_US

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