Evaluation of central and peripheral neuropathy in patients with chronic obstructive pulmonary disease

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dc.authoridAdil Can Güngen / 0000-0002-2676-723X
dc.authorscopusidBelma Doğan Güngen / 56841681700
dc.authorscopusidAdil Can Güngen / 56682130600
dc.authorwosidBelma Doğan Güngen / JMX-6710-2023
dc.authorwosidAdil Can Güngen / AAO-2470-2020
dc.contributor.authorAras, Yesim Guzey
dc.contributor.authorAydemir, Yusuf
dc.contributor.authorDoğan Güngen, Belma
dc.contributor.authorGüngen, Adil Can
dc.date.accessioned2020-08-30T20:07:52Z
dc.date.available2020-08-30T20:07:52Z
dc.date.issued2018
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractBackground: The aim of the study was to investigate the frequency and characteristics of peripheral nervous system (PNS) and central nervous system (CNS) involvement in COPD. Methods: The study included 41 COPD patients and 41 healthy volunteers. Electrophysiological studies were carried out: electromyography (EMG) and visual evoked potentials (VEPs). The median nerve, ulnar nerve, common peroneal nerve, and tibial nerve were evaluated for latency, amplitude, and conduction velocity. Results: The mean age of patients with COPD was 61.8 years and disease duration 10.3 years. There was no difference between patient and control groups in terms of age, BMI, smoking status, or biochemical parameters. Upon VEP examination, latencies were significantly prolonged and amplitudes shortened in the patient group compared to the control group. In EMG measurements, conduction velocity and amplitudes in all nerves were low in the patient group. Similarly, latencies in all nerves were higher in patients with COPD. Conclusion: Central and peripheral nervous system involvement could develop in patients with moderate-severe COPD, and these patients should be monitored for neuropathic changes in combination with neurological examination.en_US
dc.identifier.citationAras, Y. G., Aydemir, Y., Güngen, B. D., & Güngen, A. C. (2018). Evaluation of central and peripheral neuropathy in patients with chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease, 13, 1857.en_US
dc.identifier.doi10.2147/COPD.S159738en_US
dc.identifier.endpage1862en_US
dc.identifier.issn1178-2005en_US
dc.identifier.pmid29922052en_US
dc.identifier.scopus2-s2.0-85048300080en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1857en_US
dc.identifier.urihttps://doi.org/10.2147/COPD.S159738
dc.identifier.urihttps://hdl.handle.net/20.500.12713/844
dc.identifier.volume13en_US
dc.identifier.wosWOS:000434762100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDoğan Güngen, Belmaen_US
dc.institutionauthorGüngen, Adil Canen_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofInternational Journal of Chronic Obstructive Pulmonary Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic Obstructive Pulmonary Diseaseen_US
dc.subjectVisual Evoked Potentialsen_US
dc.subjectElectromyographyen_US
dc.subjectPeripheral Neuropathyen_US
dc.subjectElectrophysiological Studyen_US
dc.titleEvaluation of central and peripheral neuropathy in patients with chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

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