XEN gel stent versus trabeculectomy: short-term effects on corneal endothelial cells

dc.authoridFatih Atmaca / 0000-0002-9416-1432
dc.authorscopusidFatih Atmaca / 54894002500
dc.authorwosidFatih Atmaca / EOG-0720-2022
dc.contributor.authorOlgun, Ali
dc.contributor.authorDüzgün, Eyüp
dc.contributor.authorMavi Yıldız, Ayşegül
dc.contributor.authorAtmaca, Fatih
dc.contributor.authorYıldız, A. Atakhan
dc.contributor.authorŞendul, S.Yekta
dc.date.accessioned2020-08-30T20:01:35Z
dc.date.available2020-08-30T20:01:35Z
dc.date.issued2020
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Ameliyathane Hizmetleri Bölümüen_US
dc.descriptionAtmaca, Fatih (isu author)
dc.description.abstractPurpose: To compare the short-term changes in corneal endothelial cells after trabeculectomy or XEN Gel Stent implantation. Design: Prospective, interventional, comparative study. Methods: Changes in corneal endothelium in patients that underwent XEN Gel Stent implantation or trabeculectomy were prospectively evaluated. Eighty eyes of 62 diagnosed with open-angle glaucoma were divided into two the trabeculectomy and XEN Gel Stent groups. Corneal specular microscopy was performed at the central cornea using a noncontact specular microscope preoperatively and 3 months after surgery. Results: The baseline mean corneal endothelial cell density in the trabeculectomy group was 2390.3 ± 324.8 cells/mm2, and this was significantly reduced to 2148 ± 352.5 cells/mm2 3 months after surgery, representing a cell loss of 10.0% (p < 0.001). The baseline mean corneal endothelial cell density in the XEN Gel Stent group was 2156.2 ±559.7 cells/mm2, and this was significantly reduced to 2098.4 ± 556.2 cells/mm2 3 months after surgery, representing a cell loss of 2.1% (p = 0.002). The corneal endothelial cell density change rate of the trabeculectomy group (?10.0% ± 9.7%) was statistically higher than the XEN Gel Stent group (?2.1% ± 13.8%) (p = 0.002). A statistically significant difference was observed in the trabeculectomy group between the baseline and postoperative values in the coefficient of variation (p = 0.029). Conclusion: Trabeculectomy caused more endothelial cell damage than XEN Gel Stent implantation in the short-term follow-up period. The XEN Gel Stent may be the treatment of choice in patients with a significantly low preoperative corneal endothelial cell density. © The Author(s) 2020.en_US
dc.identifier.citationOlgun, A., Duzgun, E., Yildiz, A. M., Atmaca, F., Yildiz, A. A., & Sendul, S. Y. (2020). XEN Gel Stent versus trabeculectomy: Short-term effects on corneal endothelial cells. European Journal of Ophthalmology, 1120672120924339.en_US
dc.identifier.doi10.1177/1120672120924339en_US
dc.identifier.issn1120-6721en_US
dc.identifier.pmid32452237en_US
dc.identifier.scopus2-s2.0-85085361450en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1177/1120672120924339
dc.identifier.urihttps://hdl.handle.net/20.500.12713/302
dc.identifier.wosWOS:000536582100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtmaca, Fatihen_US
dc.language.isoenen_US
dc.publisherSAGE Publications Ltden_US
dc.relation.ispartofEuropean Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCornea/External Diseaseen_US
dc.subjectDiagnostic Techniquesen_US
dc.subjectExamination Techniquesen_US
dc.subjectGlaucomaen_US
dc.subjectGlaucoma Incisional Surgeryen_US
dc.subjectOpen-Angle Glaucomaen_US
dc.subjectSpecular Microscopyen_US
dc.titleXEN gel stent versus trabeculectomy: short-term effects on corneal endothelial cellsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
73s.pdf
Boyut:
543.74 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text