XEN gel stent versus trabeculectomy: short-term effects on corneal endothelial cells
dc.authorid | Fatih Atmaca / 0000-0002-9416-1432 | |
dc.authorscopusid | Fatih Atmaca / 54894002500 | |
dc.authorwosid | Fatih Atmaca / EOG-0720-2022 | |
dc.contributor.author | Olgun, Ali | |
dc.contributor.author | Düzgün, Eyüp | |
dc.contributor.author | Mavi Yıldız, Ayşegül | |
dc.contributor.author | Atmaca, Fatih | |
dc.contributor.author | Yıldız, A. Atakhan | |
dc.contributor.author | Şendul, S.Yekta | |
dc.date.accessioned | 2020-08-30T20:01:35Z | |
dc.date.available | 2020-08-30T20:01:35Z | |
dc.date.issued | 2020 | |
dc.department | İstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Ameliyathane Hizmetleri Bölümü | en_US |
dc.description | Atmaca, Fatih (isu author) | |
dc.description.abstract | Purpose: To compare the short-term changes in corneal endothelial cells after trabeculectomy or XEN Gel Stent implantation. Design: Prospective, interventional, comparative study. Methods: Changes in corneal endothelium in patients that underwent XEN Gel Stent implantation or trabeculectomy were prospectively evaluated. Eighty eyes of 62 diagnosed with open-angle glaucoma were divided into two the trabeculectomy and XEN Gel Stent groups. Corneal specular microscopy was performed at the central cornea using a noncontact specular microscope preoperatively and 3 months after surgery. Results: The baseline mean corneal endothelial cell density in the trabeculectomy group was 2390.3 ± 324.8 cells/mm2, and this was significantly reduced to 2148 ± 352.5 cells/mm2 3 months after surgery, representing a cell loss of 10.0% (p < 0.001). The baseline mean corneal endothelial cell density in the XEN Gel Stent group was 2156.2 ±559.7 cells/mm2, and this was significantly reduced to 2098.4 ± 556.2 cells/mm2 3 months after surgery, representing a cell loss of 2.1% (p = 0.002). The corneal endothelial cell density change rate of the trabeculectomy group (?10.0% ± 9.7%) was statistically higher than the XEN Gel Stent group (?2.1% ± 13.8%) (p = 0.002). A statistically significant difference was observed in the trabeculectomy group between the baseline and postoperative values in the coefficient of variation (p = 0.029). Conclusion: Trabeculectomy caused more endothelial cell damage than XEN Gel Stent implantation in the short-term follow-up period. The XEN Gel Stent may be the treatment of choice in patients with a significantly low preoperative corneal endothelial cell density. © The Author(s) 2020. | en_US |
dc.identifier.citation | Olgun, A., Duzgun, E., Yildiz, A. M., Atmaca, F., Yildiz, A. A., & Sendul, S. Y. (2020). XEN Gel Stent versus trabeculectomy: Short-term effects on corneal endothelial cells. European Journal of Ophthalmology, 1120672120924339. | en_US |
dc.identifier.doi | 10.1177/1120672120924339 | en_US |
dc.identifier.issn | 1120-6721 | en_US |
dc.identifier.pmid | 32452237 | en_US |
dc.identifier.scopus | 2-s2.0-85085361450 | en_US |
dc.identifier.scopusquality | Q2 | en_US |
dc.identifier.uri | https://doi.org/10.1177/1120672120924339 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12713/302 | |
dc.identifier.wos | WOS:000536582100001 | en_US |
dc.identifier.wosquality | Q3 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.institutionauthor | Atmaca, Fatih | en_US |
dc.language.iso | en | en_US |
dc.publisher | SAGE Publications Ltd | en_US |
dc.relation.ispartof | European Journal of Ophthalmology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Cornea/External Disease | en_US |
dc.subject | Diagnostic Techniques | en_US |
dc.subject | Examination Techniques | en_US |
dc.subject | Glaucoma | en_US |
dc.subject | Glaucoma Incisional Surgery | en_US |
dc.subject | Open-Angle Glaucoma | en_US |
dc.subject | Specular Microscopy | en_US |
dc.title | XEN gel stent versus trabeculectomy: short-term effects on corneal endothelial cells | en_US |
dc.type | Article | en_US |
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