Efficacy and mechanisms of transcranial electrical stimulation in headache disorders

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dc.authoridSacit Karamürsel / 0000-0002-7534-9392
dc.authorscopusidSacit Karamürsel / 7004361830
dc.authorwosidSacit Karamürsel / O-9371-2019
dc.contributor.authorŞirin, Tuba Cerrahoğlu
dc.contributor.authorAksu, Serkan
dc.contributor.authorKurt, Adnan
dc.contributor.authorKaramürsel, Sacit
dc.contributor.authorBaykan, Betül
dc.date.accessioned2020-08-30T20:06:46Z
dc.date.available2020-08-30T20:06:46Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractHeadache is the one of the most common problems contributing to suffering worldwide and sometimes it causes disability. Some patients are unable to use the drugs for various reasons and some are resistant to the pharmacological treatment. Therefore, additional effective non-pharmacological treatments are sought.Transcranial electrical stimulation techniques have been developed as potential therapeutic options. Among these techniques, transcranial direct current stimulation (tDCS) is the only technique studied for the treatment of headache. TDCS is a neurophysiological technique with multifarious advantages encompassing its low-cost, high tolerability and acceptability, comfortable application and the opportunity to use concomitantly with other treatments. Steadily increasing interest in tDCS stems from the multidisciplinary advances in neuroscientific backgrounds of neuropsychiatric diseases. Even though exact mechanisms behind benefits of tDCS have not yet been clearly disclosed, changes in multitudinous chemical and physiological parameters have been demonstrated. The purpose of this review is to summarize what is currently known regarding the effects of tDCS on the treatment of headache focusing mostly on migraine. Herein, tDCS procedures that may be helpful for primary headache treatment were described. TDCS has shown promise for effectively treating primary headaches with no severe adverse effects. The findings indicate that the analgesic effects of tDCS can last for a long period and can occur after the time of stimulation. Additional research is required for the determination of optimized stimulation protocols in each specific headache disorder.en_US
dc.description.sponsorshipIstanbul University Scientific Research Projects UnitIstanbul University [BAP-33704]en_US
dc.description.sponsorshipWe acknowledge Istanbul University Scientific Research Projects Unit for the funding acquired by the Project ID BAP-33704.en_US
dc.identifier.citationSirin, T. C., Aksu, S., Kurt, A., Karamursel, S., & Baykan, B. (2019). Efficacy and mechanisms of transcranial electrical stimulation in headache disorders.en_US
dc.identifier.doi10.5152/NSN.2019.12441en_US
dc.identifier.endpage68en_US
dc.identifier.issn2636-865Xen_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85070554582en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage57en_US
dc.identifier.trdizinid353368en_US
dc.identifier.urihttps://doi.org/10.5152/NSN.2019.12441
dc.identifier.urihttps://hdl.handle.net/20.500.12713/617
dc.identifier.volume36en_US
dc.identifier.wosWOS:000472885900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKaramürsel, Saciten_US
dc.language.isoenen_US
dc.publisherEge Univen_US
dc.relation.ispartofNeurological Sciences and Neurophysiologyen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeadacheen_US
dc.subjectMigraineen_US
dc.subjectTranscranial Direct Current Stimulationen_US
dc.subjectTranscranial Electrical Stimulationen_US
dc.titleEfficacy and mechanisms of transcranial electrical stimulation in headache disordersen_US
dc.typeReview Articleen_US

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