Prognostic factors, treatment methods and survival time in hepatocellular carcinoma: A decade of experience at a single center

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dc.authoridMurat Korkmaz / 0000-0002-9333-782X
dc.authorwosidMurat Korkmaz / AAM-1330-2020
dc.contributor.authorSunar, Ali
dc.contributor.authorKorkmaz, Murat
dc.date.accessioned2022-07-25T13:39:58Z
dc.date.available2022-07-25T13:39:58Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractBackground and Aim: The objective of this study was to investigate the etiology, prognostic factors, treatment methods, and effects of treatment on survival in cases of hepatocellular carcinoma (HCC). Materials and Methods: This was a retrospective study of 158 patients diagnosed with HCC at a single hospital between the years 2000 and 2010. Results: The etiological factor of HCC was the hepatitis B virus (HBV) in 53.2% of the cases, the hepatitis C virus (HCV) in 21.5%, alcohol use in 6.3%, HBV+alcohol in 5.7%, HCV+alcohol in 1.9%, HBV+HCV in 1.9%, and the cause was unknown in 9.5%. Of the 158 patients, 120 were treated at the study hospital, and complete follow-up data were available for 81. The mean length of follow-up was 17.9 months (range: 0.6–124 months). Multivariate analysis indicated that a lesion size >5 cm, Child-Pugh class C, a high creatinine level, and a distant metastasis were prognostic factors of reduced survival. Conclusion: HBV was the most frequent cause of HCC in this study group, followed by HCV. The most effective treatment methods for survival were liver transplantation and hepatic resection. A lesion size >5 cm, Child-Pugh class C, a high creatinine level, and distant metastasis were independent poor prognostic factors for survival.en_US
dc.identifier.citationSunar A, Korkmaz M. Prognostic factors, treatment methods and survival time in hepatocellular carcinoma: A decade of experience at a single center. Hepatol Forum. 2021 May 24;2(2):49-54. doi: 10.14744/hf.2021.2021.0001. PMID: 35783903; PMCID: PMC9138917.en_US
dc.identifier.doi10.14744/hf.2021.2021.0001en_US
dc.identifier.endpage54en_US
dc.identifier.issn1307-5888en_US
dc.identifier.issue2en_US
dc.identifier.pmid35783903en_US
dc.identifier.startpage49en_US
dc.identifier.urihttp://doi.org/10.14744/hf.2021.2021.0001
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3041
dc.identifier.volume2en_US
dc.identifier.wosWOS:000863547600003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKorkmaz, Murat
dc.language.isoenen_US
dc.publisherPMCen_US
dc.relation.ispartofHepatology Forumen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHepatitis B Virusen_US
dc.subjectHepatocellular Carcinomaen_US
dc.subjectLiver Transplantationen_US
dc.titlePrognostic factors, treatment methods and survival time in hepatocellular carcinoma: A decade of experience at a single centeren_US
dc.typeArticleen_US

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