Newborn screening for sickle cell anemia in Antalya, Türkiye

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dc.contributor.authorOzturk, Zeynep
dc.contributor.authorKupesiz, O. Alphan
dc.contributor.authorKarasu, Gulsun
dc.contributor.authorUygun, Vedat
dc.contributor.authorOygur, Nihal
dc.contributor.authorYesilipek, M. Akif
dc.date.accessioned2024-05-19T14:46:00Z
dc.date.available2024-05-19T14:46:00Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractBackground. In a screening study conducted on adults, the prevalence of sickle cell traits in Antalya was found to be 0.24%. Since no screening studies have been conducted in the neonatal period in our region, the exact incidence has not been determined. In this study, we aim to report our experience of neonatal screening for sickle cell disease in Antalya, Turkiye.Methods. During a 14-month period, 2562 heel prick blood samples, taken on filter paper from Akdeniz University Hospital, Antalya Education and Research Hospital and Antalya Ataturk State Hospital and four other healthcare centers, were studied using the high pressure liquid chromatography method. Blood samples were studied using the 'Sickle Cell Short Program' test method on a Bio Rad Variant device.Results. In the study, no patients with sickle cell disease were identified. Four newborns who were sickle cell carriers (0.15%) and two newborns who were Hemoglobin D carriers (0.08 %), were found. Conclusion.Considering the efficiency and cost calculations made as a result of the data obtained from our study, it was concluded that sickle cell screening would not be effective in newborns. It seems more effective and economical to screen the children of parents, who are found to be at risk for Hemoglobin S carriage as a result of premarital tests.en_US
dc.description.sponsorshipScientific Research Projects Coordination Unit of Akdeniz University [2004.02.0122.004]; Turkish Society of Hematology [06/F]en_US
dc.description.sponsorshipSource of funding This study was supported by the Scientific Research Projects Coordination Unit of Akdeniz University and was carried out as a master's thesis (Project number: 2004.02.0122.004) by Z. Ozturk and presented to Akdeniz University Health Sciences Institute. This study was also supported by the Turkish Society of Hematology (Project number: 06/F) .en_US
dc.identifier.doi10.24953/turkjped.2023.17
dc.identifier.endpage963en_US
dc.identifier.issn0041-4301
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85182095347en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage959en_US
dc.identifier.trdizinid1221608en_US
dc.identifier.urihttps://doi.org10.24953/turkjped.2023.17
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1221608
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5416
dc.identifier.volume65en_US
dc.identifier.wosWOS:001140242600008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectNewborn Screeningen_US
dc.subjectSickle Cellen_US
dc.subjectHemoglobinopathyen_US
dc.subjectTurkiye.en_US
dc.titleNewborn screening for sickle cell anemia in Antalya, Türkiyeen_US
dc.typeArticleen_US

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