COVID-19 in hospitalized infants aged under 3 months: multi-center experiences across Turkey

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dc.authoridSutcu, Murat/0000-0002-2078-9796
dc.authoridCelik, Binnaz tekatli/0000-0001-8852-0067
dc.authoridkaba, özge/0000-0002-8381-3255
dc.authoridCanizci Erdemli, Pinar/0000-0002-6200-3173
dc.authorwosidumit, zuhal/JXL-1538-2024
dc.authorwosidSutcu, Murat/AAR-5212-2020
dc.authorwosidCelik, Binnaz tekatli/JLL-1388-2023
dc.authorwosidOzkalay Yılmaz, Nisel/AAE-2293-2021
dc.authorwosidAygun, Deniz/AAC-9239-2021
dc.authorwosidkaba, özge/AAU-5309-2020
dc.contributor.authorUstundag, Gulnihan
dc.contributor.authorKaradag-Oncel, Eda
dc.contributor.authorKara-Ulu, Nursel
dc.contributor.authorPolat, Meltem
dc.contributor.authorSali, Enes
dc.contributor.authorCakir, Deniz
dc.contributor.authorSahin, Aslihan
dc.date.accessioned2024-05-19T14:39:39Z
dc.date.available2024-05-19T14:39:39Z
dc.date.issued2024
dc.departmentİstinye Üniversitesien_US
dc.description.abstractTo investigate coronavirus disease 2019 (COVID-19) in infants aged 0 to 3 months because there is currently a significant gap in the literature on the subject. A cross-sectional study was conducted with the involvement of 19 medical centers across Turkey and 570 infants. The majority of the patients were male (58.2%), and the three most common symptoms were fever (78.2%), cough (44.6%), and feeding intolerance (39.9%). The results showed that a small percentage of infants had positive blood (0.9%) or urine cultures (10.2%). Most infants presented with fever (78.2%). Children without underlying conditions (UCs) had mostly a complicated respiratory course and a normal chest radiography. Significant more positive urine culture rates were observed in infants with fever. A higher incidence of respiratory support requirements and abnormal chest findings were seen in infants with chronic conditions. These infants also had a longer hospital stay than those without chronic conditions. Conclusions: Our study discloses the clinical observations and accompanying bacterial infections found in infants aged under 3 months with COVID-19. These findings can shed light on COVID-19 in infancy for physicians because there is limited clinical evidence available.What is Known:center dot COVID-19 in infants and older children has been seen more mildly than in adults.center dot The most common symptoms of COVID-19 in infants are fever and cough, as in older children and adults. COVID-19 should be one of the differential diagnoses in infants with fever.What is New:center dot Although most infants under three months had fever, the clinical course was uneventful and respiratory complications were rarely observed in healthy children.center dot Infants with underlying conditions had more frequent respiratory support and abnormal chest radiography and stayed longer in the hospital.en_US
dc.identifier.doi10.1007/s00431-023-05329-x
dc.identifier.endpage1162en_US
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.issue3en_US
dc.identifier.pmid37971516en_US
dc.identifier.scopus2-s2.0-85176754655en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1153en_US
dc.identifier.urihttps://doi.org10.1007/s00431-023-05329-x
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4823
dc.identifier.volume183en_US
dc.identifier.wosWOS:001103157100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectBreastfeedingen_US
dc.subjectChildrenen_US
dc.subjectClinical Presentationen_US
dc.subjectCovid-19en_US
dc.subjectInfantsen_US
dc.subjectNeonatesen_US
dc.titleCOVID-19 in hospitalized infants aged under 3 months: multi-center experiences across Turkeyen_US
dc.typeArticleen_US

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