The association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: a cardiac magnetic resonance study

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dc.authoridgüler, arda/0000-0002-5763-6785
dc.authoridMemic Sancar, Kadriye/0000-0003-1350-215X;
dc.authorwosidgüler, arda/HJY-2884-2023
dc.authorwosidMemic Sancar, Kadriye/GVU-1673-2022
dc.authorwosidbabur guler, gamze/HKN-4198-2023
dc.contributor.authorGuler, Arda
dc.contributor.authorTopel, Cagdas
dc.contributor.authorSahin, Ahmet Anil
dc.contributor.authorAydin, Sinem
dc.contributor.authorGuler, Ekrem
dc.contributor.authorSancar, Kadriye Memic
dc.contributor.authorCansever, Aysel Turkvatan
dc.date.accessioned2024-05-19T14:39:50Z
dc.date.available2024-05-19T14:39:50Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractPurpose: Hypertrophic cardiomyopathy (HCM) is related with structural and pathologic changes in the left atrium (LA) and left ventricle (LV). The aim of this study was to explore the association between LA mechanics and LV charac-teristics in patients with HCM using cardiac magnetic resonance feature tracking (CMR-FT). Material and methods: A total of 76 patients with HCM and 26 healthy controls were included in the study. The pa-rameters including the extent of LV late gadolinium enhancement (LGE-%) and the LV early diastolic longitudinal strain rate (edLSR) were assessed for LV. LA conduit, booster, and reservoir functions were assessed by LA fractional volumes and strain analyses using CMR-FT. HCM patients were classified as HCM patients without LGE, with mild LGE-% (0% < LGE-% >= 10%), and prominent LGE-% (10% < LGE-%).Results: HCM patients had worse LA functions compared with the controls (p < 0.05). The majority of LA functional indices were more impaired in HCM patients with regard to LGE. LA volumes were higher in HCM patients with prominent LGE-% compared with HCM patients with mild LGE-% (p < 0.05). However, only a minority of LA functional parameters differed between the 2 groups. LA strain parameters showed weak to modest correlations with LV LGE-% and LV edLSR.Conclusions: LV characteristics, to some extent, influence LA mechanics, but they might not be the only factor induc-ing LA dysfunction in patients with HCM.en_US
dc.identifier.doi10.5114/pjr.2023.125213
dc.identifier.endpagee112en_US
dc.identifier.issn0137-7183
dc.identifier.issn1899-0967
dc.identifier.pmid36910882en_US
dc.identifier.scopus2-s2.0-85149405781en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpagee103en_US
dc.identifier.urihttps://doi.org10.5114/pjr.2023.125213
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4857
dc.identifier.volume88en_US
dc.identifier.wosWOS:000938453200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherInt Scientific Information Incen_US
dc.relation.ispartofPolish Journal of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectCardiac Magnetic Resonanceen_US
dc.subjectHypertrophic Cardiomyopathyen_US
dc.subjectLeft Atriumen_US
dc.subjectLate Gadolinium Enhancementen_US
dc.titleThe association of left atrial mechanics with left ventricular morphology in patients with hypertrophic cardiomyopathy: a cardiac magnetic resonance studyen_US
dc.typeArticleen_US

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