Managing recurrent parvovirus B19-associated anemia after a pediatric kidney transplant
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A 13-year-old girl who had a kidney transplant four weeks prior presented with a 10-day history of fatigue, paleness, and headache. On physical examination, tachycardia and paleness were noted. Laboratory testing was notable for severe anemia and mild leukopenia and thrombocytopenia. Polymerase chain reaction (PCR) test for Epstein-Barr virus (EBV) and cytomegalovirus (CMV) were negative and for parvovirus B19 (PVB19) was positive. Despite lower immunosuppression and administration of intravenous immunoglobulin (IVIG) it persisted for 15 months, and frequent red blood cell transfusions were needed. PVB19 is a less common but significant complication. The patient's clinical course demonstrates the importance of this complication and the challenges in its management. A notable void exists in the literature regarding standardized treatment protocols for PVB19-induced recurrent anemia after kidney transplant. This case indicates the need for further research and consensus to guide effective clinical interventions in similar cases.
Açıklama
Anahtar Kelimeler
Anemia, Immunosuppression, Kidney Transplant, Parvovirus B19, Treatment Protocols
Kaynak
Pediatric nephrology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
39
Sayı
10
Künye
Sabanci, M., Taşdemir, M., Öksüz, B., Altuner Torun, Y., Sütçü, M., & Özkaya, O. (2024). Managing recurrent parvovirus B19-associated anemia after a pediatric kidney transplant. Pediatric Nephrology, 1-3.
