Efficacy of multidisciplinary approach in thyroid nodules: analysis of factors used for predicting malignancy

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dc.authoridSavaş Volkan Kişioǧlu / 0000-0002-7742-048Xen_US
dc.authorscopusidSavaş Volkan Kişioǧlu / 57216558997
dc.authorwosidSavaş Volkan Kişioǧlu / AAT-3031-2021
dc.contributor.authorKişio?lu, Savaş Volkan
dc.contributor.authorAtacan, Hüseyin
dc.contributor.authorÇakır, Emel
dc.contributor.authorOğuz, Şükrü
dc.contributor.authorKaraküllükçü, Serdar
dc.contributor.authorErsöz, Halil Önder
dc.date.accessioned2022-11-11T08:13:29Z
dc.date.available2022-11-11T08:13:29Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Hastaneen_US
dc.description.abstractObjective: To date, numerous molecular tests have been developed for preoperative evaluation of thyroid nodules. Nevertheless, these tests cannot be administered in many centers due to their imprecise diagnoses and high costs. The present study aimed to investigate the effect of making surgical decisions in a panel through a multidisciplinary approach after clinical, ultrasonographic, and pathological evaluation of nodules on the accuracy of the decisions. Methods: The retrospective study included patients with thyroid nodules who underwent preoperative ultrasonography followed by fine-needle aspiration biopsy, which was confirmed by postoperative pathological examinations between January 2017 and January 2019. The relationship between ultrasonography features of nodules and malignancy was analyzed. A comparison was performed between patients who were referred for surgery through the multidisciplinary versus non-multidisciplinary approach. Results: A total of 255 nodules in 211 patients were evaluated in the study. The prevalence of malignancy was 100% in nodules with hypoechogenicity + microcalcification + margin irregularity (P <.001). The likelihood of malignancy was significantly higher in dual combinations of these 3 adverse conditions (P <.001 for all). Margin irregularity was found to be the most predictive model for malignancy (CI: 1.9-13.8, odds ratio: 5.249, P <.001). The multidisciplinary approach was superior to the non-multidisciplinary approach in the detection of malignancy (P =.008). Conclusion: Margin irregularity had the highest predictive value for the detection of malignancy. Employing the multidisciplinary approach in preoperative evaluation of thyroid nodules can be highly effective in detecting malignancy and preventing unnecessary surgery.en_US
dc.identifier.citationVolkan, K. S., Atacan, H., Cakir, E., Oguz, S., Karakullukcu, S., & Onder, E. H. (2022). Efficacy of multidisciplinary approach in thyroid nodules: analysis of factors used for predicting malignancy. In Endocrine Abstracts (Vol. 26). Bioscientifica.en_US
dc.identifier.doi10.5152/tjem.2022.22020en_US
dc.identifier.endpage130en_US
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85141036757en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage125en_US
dc.identifier.trdizinid1124136en_US
dc.identifier.urihttps://doi.org/10.5152/tjem.2022.22020
dc.identifier.urihttps://hdl.handle.net/20.500.12713/3326
dc.identifier.volume26en_US
dc.identifier.wosWOS:000861099600005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.institutionauthorKişioǧlu, Savaş Volkan
dc.language.isoenen_US
dc.publisherTURKIYE KLINIKLERIen_US
dc.relation.ispartofTURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFine-needle Aspirationen_US
dc.subjectIrregular Marginen_US
dc.subjectMultidisciplinary Approachen_US
dc.subjectRisk of Malignancyen_US
dc.subjectThyroid Canceren_US
dc.subjectThyroid Nodulesen_US
dc.titleEfficacy of multidisciplinary approach in thyroid nodules: analysis of factors used for predicting malignancyen_US
dc.typeArticleen_US

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