COVID-19: vaccination vs. hospitalization

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dc.authoridTekin Akpolat / 0000-0003-3104-9205
dc.authorscopusidTekin Akpolat / 7004571672
dc.authorwosidTekin Akpolat / IAM-7772-2023
dc.contributor.authorUzun, Oğuz
dc.contributor.authorAkpolat, Tekin
dc.contributor.authorVarol, Ayhan
dc.contributor.authorTuran, Sema
dc.contributor.authorBektaş, Şerife Gökbulut
dc.date.accessioned2022-01-18T08:43:40Z
dc.date.available2022-01-18T08:43:40Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective Vaccination is the most efcient way to control the coronavirus disease 2019 (COVID-19) pandemic, but vaccination rates remain below the target level in most countries. This multicenter study aimed to evaluate the vaccination status of hospitalized patients and compare two diferent booster vaccine protocols. Setting Inoculation in Turkey began in mid-January 2021. Sinovac was the only available vaccine until April 2021, when BioNTech was added. At the beginning of July 2021, the government ofered a third booster dose to healthcare workers and people aged>50 years who had received the two doses of Sinovac. Of the participants who received a booster, most chose BioNTech as the third dose. Methods We collected data from 25 hospitals in 16 cities. Patients hospitalized between August 1 and 10, 2021, were included and categorized into eight groups according to their vaccination status. Results We identifed 1401 patients, of which 529 (37.7%) were admitted to intensive care units. Nearly half (47.8%) of the patients were not vaccinated, and those with two doses of Sinovac formed the second largest group (32.9%). Hospitalizations were lower in the group which received 2 doses of Sinovac and a booster dose of BioNTech than in the group which received 3 doses of Sinovac. Conclusion Efective vaccinations decreased COVID-19-related hospitalizations. The efcacy after two doses of Sinovac may decrease over time; however, it may be enhanced by adding a booster dose. Moreover, unvaccinated patients may be persuaded to undergo vaccination.en_US
dc.identifier.citationUzun, O., Akpolat, T., Varol, A., Turan, S., Bektas, S. G., Cetinkaya, P. D., . . . Itil, O. (2022). COVID-19: Vaccination vs. hospitalization. Infectionen_US
dc.identifier.doi10.1007/s15010-021-01751-1en_US
dc.identifier.issn0300-8126en_US
dc.identifier.pmid34984646en_US
dc.identifier.scopus2-s2.0-85122327560en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://10.1007/s15010-021-01751-1
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2391
dc.identifier.wosWOS:000738586900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAkpolat, Tekin
dc.language.isoenen_US
dc.publisherSpringer Science and Business Media Deutschland GmbHen_US
dc.relation.ispartofINFECTIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19 pandemicen_US
dc.subjectCOVID-19 vaccineen_US
dc.subjectSinoVacen_US
dc.subjectBioNTechen_US
dc.titleCOVID-19: vaccination vs. hospitalizationen_US
dc.typeArticleen_US

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