Autophagy and Biomaterials: A Brief Overview of the Impact of Autophagy in Biomaterial Applications

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dc.authoridGhavami, Saeid/0000-0001-5948-508X
dc.authoridZarepour, Atefeh/0000-0002-0347-5840
dc.authoridZarrabi, Ali/0000-0003-0391-1769
dc.authorwosidGhavami, Saeid/GLT-0606-2022
dc.authorwosidZarepour, Atefeh/AAH-9225-2020
dc.authorwosidZarrabi, Ali/U-2602-2019
dc.contributor.authorPirmoradi, Leila
dc.contributor.authorShojaei, Shahla
dc.contributor.authorGhavami, Saeid
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorZarrabi, Ali
dc.date.accessioned2024-05-19T14:39:27Z
dc.date.available2024-05-19T14:39:27Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractMacroautophagy (hereafter autophagy), a tightly regulated physiological process that obliterates dysfunctional and damaged organelles and proteins, has a crucial role when biomaterials are applied for various purposes, including diagnosis, treatment, tissue engineering, and targeted drug delivery. The unparalleled physiochemical properties of nanomaterials make them a key component of medical strategies in different areas, such as osteogenesis, angiogenesis, neurodegenerative disease treatment, and cancer therapy. The application of implants and their modulatory effects on autophagy have been known in recent years. However, more studies are necessary to clarify the interactions and all the involved mechanisms. The advantages and disadvantages of nanomaterial-mediated autophagy need serious attention in both the biological and bioengineering fields. In this mini-review, the role of autophagy after biomaterial exploitation and the possible related mechanisms are explored.en_US
dc.description.sponsorship1002-Short Term R&D Funding Program of The Scientific and Technological Research Council of Turkiye (TUBITAK) [221Z107]; Turkey-Iran Bilateral Cooperation Program of The Scientific and Technological Research Council of Turkiye (TUBITAK) [121N152]; University of Manitoba UCRP operating grant [54304]en_US
dc.description.sponsorshipAli Zarrabi acknowledges funding support from the 1002-Short Term R&D Funding Program (Project No: 221Z107) and the Turkey-Iran Bilateral Cooperation Program (Project No: 121N152) of The Scientific and Technological Research Council of Turkiye (TUBITAK). Saeid Ghavmi was funded by the University of Manitoba UCRP operating grant (54304).en_US
dc.identifier.doi10.3390/pharmaceutics15092284
dc.identifier.issn1999-4923
dc.identifier.issue9en_US
dc.identifier.pmid37765253en_US
dc.identifier.scopus2-s2.0-85172697180en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.3390/pharmaceutics15092284
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4781
dc.identifier.volume15en_US
dc.identifier.wosWOS:001074406300001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofPharmaceuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectBiomaterialsen_US
dc.subjectAutophagyen_US
dc.subjectOsteogenesisen_US
dc.subjectAngiogenesisen_US
dc.subjectNeurodegenerative Diseasesen_US
dc.subjectTumor Cellsen_US
dc.titleAutophagy and Biomaterials: A Brief Overview of the Impact of Autophagy in Biomaterial Applicationsen_US
dc.typeReview Articleen_US

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