Risk factors affecting benign anastomotic stricture in anterior and low anterior resections for colorectal cancer: a single-center retrospective cohort study

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dc.authoridFerahman, Sina/0000-0003-1160-9156
dc.authoridDural, Ahmet Cem/0000-0003-3479-725X
dc.authorwosidFerahman, Sina/ABI-4440-2020
dc.authorwosidDural, Ahmet Cem/P-2006-2014
dc.contributor.authorSurek, Ahmet
dc.contributor.authorDonmez, Turgut
dc.contributor.authorGemici, Eyup
dc.contributor.authorDural, Ahmet Cem
dc.contributor.authorAkarsu, Cevher
dc.contributor.authorKaya, Arif
dc.contributor.authorFerahman, Sina
dc.date.accessioned2024-05-19T14:40:14Z
dc.date.available2024-05-19T14:40:14Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractPurpose Although not as life-threatening as anastomotic leakage, anastomotic stricture reduces the quality of life. The risk factors for such an important life complication have not been revealed. This article examines the risk factors affecting anastomotic strictures due to colorectal cancers.Methods Patients who underwent anterior and low anterior resection for colorectal cancer under elective conditions between 2015 and 2021 were included in the study. The patients were divided into two groups, those who developed anastomotic stricture and those who did not. The parameters determined between the two groups were compared, and multivariate analysis of statistically significant parameters was performed.Results A total of 375 patients were included in the study. The anastomotic stricture was detected in 36 (9.6%) patients. In the multivariate analysis, non-mobilization of the splenic flexure and a proximal clean surgical margin of < 10 cm and a distal surgical margin of < 2 cm were identified as risk factors affecting anastomotic stricture. The risk factor with the highest odds ratio in the development of anastomotic stricture is the non-mobilization of the splenic flexure (p = 0.001, OR 11.375).ConclusionIt is recommended that the mobilization of the splenic flexure to reduce the development of strictures. In addition, a clean surgical margin of 10 cm proximally and 2 cm distally and high ligation of the inferior mesenteric artery may reduce the development of stricture.en_US
dc.identifier.doi10.1007/s00464-023-10002-3
dc.identifier.endpage5255en_US
dc.identifier.issn0930-2794
dc.identifier.issn1432-2218
dc.identifier.issue7en_US
dc.identifier.pmid36964291en_US
dc.identifier.scopus2-s2.0-85150653843en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage5246en_US
dc.identifier.urihttps://doi.org10.1007/s00464-023-10002-3
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4928
dc.identifier.volume37en_US
dc.identifier.wosWOS:000958511100002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofSurgical Endoscopy and Other Interventional Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240519_kaen_US
dc.subjectColorectal Canceren_US
dc.subjectAnastomotic Strictureen_US
dc.subjectAnastomotic Stenosisen_US
dc.subjectColorectal Anastomosisen_US
dc.titleRisk factors affecting benign anastomotic stricture in anterior and low anterior resections for colorectal cancer: a single-center retrospective cohort studyen_US
dc.typeArticleen_US

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