Gold nanorods for drug and gene delivery: an overview of recent advancements

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dc.authoridAli Zarrabi / 0000-0003-0391-1769en_US
dc.authorscopusidAli Zarrabi / 23483174100
dc.authorwosidAli Zarrabi / U-2602-2019
dc.contributor.authorJahangiri-Manesh, Atieh
dc.contributor.authorMousazadeh, Marziyeh
dc.contributor.authorTaji, Shirinsadat
dc.contributor.authorBahmani, Abbas
dc.contributor.authorZarepour, Atefeh
dc.contributor.authorZarrabi, Ali
dc.contributor.authorSharifi, Esmaeel
dc.contributor.authorAzimzadeh, Mostafa
dc.date.accessioned2022-04-06T05:45:57Z
dc.date.available2022-04-06T05:45:57Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümüen_US
dc.description.abstractOver the past few decades, gold nanomaterials have shown great promise in the field of nanotechnology, especially in medical and biological applications. They have become the most used nanomaterials in those fields due to their several advantageous. However, rod-shaped gold nanoparticles, or gold nanorods (GNRs), have some more unique physical, optical, and chemical properties, making them proper candidates for biomedical applications including drug/gene delivery, photothermal/photodynamic therapy, and theranostics. Most of their therapeutic applications are based on their ability for tunable heat generation upon exposure to near-infrared (NIR) radiation, which is helpful in both NIR-responsive cargo delivery and photothermal/photodynamic therapies. In this review, a comprehensive insight into the properties, synthesis methods and toxicity of gold nanorods are overviewed first. For the main body of the review, the therapeutic applications of GNRs are provided in four main sections: (i) drug delivery, (ii) gene delivery, (iii) photothermal/photodynamic therapy, and (iv) theranostics applications. Finally, the challenges and future perspectives of their therapeutic application are discussed.en_US
dc.identifier.citationJahangiri-Manesh, A., Mousazadeh, M., Taji, S., Bahmani, A., Zarepour, A., Zarrabi, A., Sharifi, E., & Azimzadeh, M. (2022). Gold Nanorods for Drug and Gene Delivery: An Overview of Recent Advancements. Pharmaceutics, 14(3), 664.en_US
dc.identifier.doi10.3390/pharmaceutics14030664en_US
dc.identifier.issue3en_US
dc.identifier.pmid35336038en_US
dc.identifier.scopus2-s2.0-85127136935en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://10.3390/pharmaceutics14030664
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2614
dc.identifier.volume14en_US
dc.identifier.wosWOS:000774449600001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorZarrabi, Ali
dc.language.isoenen_US
dc.relation.ispartofPharmaceuticsen_US
dc.relation.publicationcategoryDiÄŸeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDrug Deliveryen_US
dc.subjectGene Therapyen_US
dc.subjectGold Nanorodsen_US
dc.subjectPhotodynamic Therapyen_US
dc.subjectPhotothermal Therapyen_US
dc.subjectPhotothermal Therapyen_US
dc.titleGold nanorods for drug and gene delivery: an overview of recent advancementsen_US
dc.typeReview Articleen_US

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