Follow-up of high-grade glial tumor; differentiation of posttreatment enhancement and tumoral enhancement by DCE-MR perfusion

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dc.authoridAyşe Aralaşmak / 0000-0001-8654-855Xen_US
dc.authorscopusidAyşe Aralaşmak / 6507596742
dc.authorwosidAyşe Aralaşmak / Y-5820-2018
dc.contributor.authorDündar, Tolga Turan
dc.contributor.authorÇetinkaya, Ezra
dc.contributor.authorYurtsever, İsmail
dc.contributor.authorUysal, Ömer
dc.contributor.authorAralaşmak, Ayşe
dc.date.accessioned2022-02-23T13:07:15Z
dc.date.available2022-02-23T13:07:15Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAbstract Purpose: To search for the utility of DCE-MRP to differentiate between posttreatment enhancement (PT) and tumoral enhancement (TM) in high-grade glial tumors. Materials and methods: Thirty-four patients with glioma (11 grade 3; 23 grade 4) were enrolled. Enhancement in the vicinity of the resection cavity demonstrated by DCE-MRP was taken into consideration. Based on the follow-up scans, reoperation or biopsy results, the enhancement type was categorized as PT or TM. Measurements were performed at the enhancing area near the resection cavity (ERC), nearby (NNA) and contralateral nonenhancing areas (CLNA). Perfusion parameters of the ERC were also subtracted from NNA and CLNA. Intragroup comparison (paired sample t-test) and intergroup comparison (Student's t-test) were made. Results: There were 7 PTs and 27 TMs. In the PT, the subtracted values of Ve and IAUC from the CLNA and NNA and the subtracted value of Kep from NNA were statistically different. In TM, all metrics were significantly different comparing the CLNA and NNA. Comparing PT with TM, Ktrans, IAUC, Kep, and subtracted values of Ktrans and IAUC from both NNA and CLNA were significantly different. Conclusions: In PT, only Ktrans values did not reveal any difference comparing NNA and CLNA. To differentiate PT from TM, Ktrans, Kep, IAUC, and subtracted values of Ktrans and IAUC from NNA and CLNA can be used. These findings are in concordance with literature.en_US
dc.identifier.citationDündar TT, Cetinkaya E, Yurtsever İ, Uysal Ö, Aralaşmak A. Follow-Up of High-Grade Glial Tumor; Differentiation of Posttreatment Enhancement and Tumoral Enhancement by DCE-MR Perfusion. Contrast Media Mol Imaging. 2022 Feb 1;2022:6948422.en_US
dc.identifier.doi10.1155/2022/6948422en_US
dc.identifier.issue6948422en_US
dc.identifier.pmid35185410en_US
dc.identifier.scopus2-s2.0-85124766652en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1155/2022/6948422
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2500
dc.identifier.volume2022en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAralaşmak, Ayşe
dc.language.isoenen_US
dc.relation.ispartofContrast Media Mol Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleFollow-up of high-grade glial tumor; differentiation of posttreatment enhancement and tumoral enhancement by DCE-MR perfusionen_US
dc.typeArticleen_US

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