Evaluating the utility of the AF Genital System test for pathogen diagnosis in acute male urethritis

Basit Öğe Kaydı
dc.authoridMehmet Sarıer / 0000-0002-8656-7416en_US
dc.authorscopusidMehmet Sarıer / 57193698943
dc.authorwosidMehmet Sarıer / B-8589-2018
dc.contributor.authorSarıer, Mehmet
dc.contributor.authorSepin, Nevgun
dc.contributor.authorEmek, Mestan
dc.contributor.authorGermen, Aysegul Tezcan
dc.contributor.authorHoscan, Mustafa Burak
dc.contributor.authorKonuk, Elcin
dc.contributor.authorTurgut, Hasan
dc.date.accessioned2022-01-27T17:49:19Z
dc.date.available2022-01-27T17:49:19Z
dc.date.issued2022en_US
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Diyaliz Bölümüen_US
dc.description.abstractThis study evaluated the effectiveness of the A.F. Genital System (Liofilchem®, Italy) in detecting pathogens compared with multiplex real- time polymerase chain reaction (PCR) in men with acute urethritis. Men diagnosed as having acute urethritis between 1 April 2021 and 31 December 2021 were included. Urethral swab samples were ob-tained for A.F. Genital System and PCR testing in a randomly determined order. The efficacy of the A.F. Genital System was analysed by comparing the results of the two tests. The study included 83 patients (mean age 34.1 ± 11.3 years). A urethritis patho-gen was detected in 69 patients (83.1%) by PCR and only 15 patients (18.1%) with the A.F. Genital System. The sensitivity of the A.F. Genital System in detecting acute urethritis pathogens was 21.7% (95% confidence interval [CI]: 13.6– 32.8), and the specificity was 100% (95% CI: 78.5– 100). Its sensitivity was 20% (95% CI: 7.1– 45.2) in the diagnosis of gonococcal urethritis and 19.1% (95% CI: 11.2– 30.4) in the diagnosis of non- gonococcal urethritis. PCR detected two or more urethritis pathogens in 9 patients (13.0%), while no polymicrobial infection was detected with the A.F. Genital System. Based on the results of multiplex real- time PCR, the A.F. Genital System had very low sensitivity in the detection of pathogens in acute male urethritis. It should be kept in mind that using this test in patients with acute urethritis may result in a high missed diagnosis rate for urethritis pathogens.en_US
dc.identifier.citationSarier, M., Sepin, N., Emek, M., Germen, A. T., Hoscan, M. B., Konuk, E., & Turgut, H. (2022). Evaluating the utility of the A.F. Genital System test for pathogen diagnosis in acute male urethritis. Andrologia, 00, e14377.en_US
dc.identifier.doi10.1111/and.14377en_US
dc.identifier.issn0303-4569en_US
dc.identifier.issn1439-0272en_US
dc.identifier.pmid35064690en_US
dc.identifier.scopus2-s2.0-85123499612en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/and.14377
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2431
dc.identifier.wosWOS:000745470000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSarıer, Mehmet
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofANDROLOGIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectA.F. Genitalen_US
dc.subjectAF Genital Systemen_US
dc.subjectDiagnosisen_US
dc.subjectNon-gonococcalen_US
dc.subjectPCRen_US
dc.subjectUrethritisen_US
dc.titleEvaluating the utility of the AF Genital System test for pathogen diagnosis in acute male urethritisen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
18.pdf
Boyut:
9.98 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Diyaliz Programı Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu