Immunology meets bioengineering: Improving the effectiveness of glioblastoma immunotherapy
Yükleniyor...
Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MDPI
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Glioblastoma (GBM) therapy has seen little change over the past two decades. Surgical excision followed by radiation and chemotherapy is the current gold standard treatment. Immunotherapy techniques have recently transformed many cancer treatments, and GBM is now at the forefront of immunotherapy research. GBM immunotherapy prospects are reviewed here, with an emphasis on immune checkpoint inhibitors and oncolytic viruses. Various forms of nanomaterials to enhance immunotherapy effectiveness are also discussed. For GBM treatment and immunotherapy, we outline the specific properties of nanomaterials. In addition, we provide a short overview of several 3D (bio)printing techniques and their applications in stimulating the GBM microenvironment. Lastly, the susceptibility of GBM cancer cells to the various immunotherapy methods will be addressed.
Açıklama
Anahtar Kelimeler
Autophagy, Glioblastoma, Immunotherapy, Nanomedicine, Nanoparticles, Oncolytic Virotherapy
Kaynak
Cancers
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
14
Sayı
15
Künye
Fekrirad Z, Barzegar Behrooz A, Ghaemi S, Khosrojerdi A, Zarepour A, Zarrabi A, Arefian E, Ghavami S. Immunology Meets Bioengineering: Improving the Effectiveness of Glioblastoma Immunotherapy. Cancers (Basel). 2022 Jul 29;14(15):3698. doi: 10.3390/cancers14153698. PMID: 35954362; PMCID: PMC9367505.
