Molecularly imprinted polymer nanoparticles for the recognition of ellagic acid
Yükleniyor...
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
WILEY
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Ellagic acid (EA) is one of the bioactive polyphenolic flavonoids found in many fruits. Over the years, various extraction methods have been developed to isolate pure EA from plant samples. These methods, however, have some disadvantages, such as low specificity and selectivity, not easy incorporation into industrial processes, and low-purification efficiency. The present study proposes an approach based on the molecular imprinting technique. We describe the nanoscale production of EA imprinted polymers for the first time. We develop a straightforward, efficient, and environmentally friendly precipitation polymerization method to synthesize molecularly imprinted polymer nanoparticles (nanoMIPs). To increase the affinity of nanoMIPs, we explore molecular interactions between EA and functional monomers before polymerization. The nanoMIPs are successfully synthesized with an excellent yield of 94.5%. The maximum binding capacity is 66.6 and 45.6 mu mol/g for EA imprinted and nonimprinted polymers, respectively. Furthermore, in the presence of quercetin, an EA analog, and other compounds in the pomegranate peel extract solution, nanoMIPs selectively retain EA. NanoMIPs will be a valuable analytical tool for separation and sensing applications, especially dispersive solid-phase extraction.
Açıklama
Anahtar Kelimeler
Biomimetic, Nanostructured Polymers, Separation Techniques
Kaynak
JOURNAL OF APPLIED POLYMER SCIENCE
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
Sayı
Künye
Yucel, N., Gulen, H., Hatir, P. C. (2022). Context Sensitive Links 1 of 1 Molecularly imprinted polymer nanoparticles for the recognition of ellagic acid. Journal of Applied Polymer Science.
