Echocardiographic findings in patients with atrial septal aneurysm: a prospective case-control study

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dc.authoridErtan Yetkin / 0000-0001-8862-750X
dc.authorscopusidErtan Yetkin / 7004009443
dc.authorwosidErtan Yetkin / AGX-3712-2022
dc.contributor.authorAtak, Ramazan
dc.contributor.authorİleri, Mehmet
dc.contributor.authorÖztürk, Selçuk
dc.contributor.authorKorkmaz, Ahmet
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2020-08-30T20:07:08Z
dc.date.available2020-08-30T20:07:08Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground. Atrial septal aneurysm (ASA) is a congenital deformity of the interatrial septum with a prevalence of 1-2% in the adult population. Although ASA has been supposed to be an incidental finding in echocardiographic examination, its structural and clinical associations have gained an increasing interest. Aim. To investigate and compare the clinical features and echocardiographic parameters between ASA patients and age- and gender-matched control group patients. Methods. 410 patients with ASA were enrolled in the study, prospectively. After the exclusion of 33 patients, the remaining 377 patients comprised the study group. The control group consisted of 377 age- and gender-matched patients without ASA. Results. Aortic valve regurgitation and mitral valve regurgitation were more often observed in patients with ASA, and percentages of patients with ascending aortic aneurysm (AAA), patent foramen ovale (PFO), and atrial septal defect (ASD) were higher in ASA patients compared to control group patients. Aortic root diameter was larger in ASA patients compared to control group patients (29.2 +/- 3.9, 28.6 +/- 3.1, p = 0.05, respectively). Ascending aorta diameter was higher in ASA patients compared to patients without ASA (44 +/- 0.3, 41.5 +/- 0.2, p = 0.02). Logistic regression analysis revealed that mitral valve regurgitation (OR: 2.05, 95% CI:1.44-2.92, p < 0.001) and PFO (OR: 11.62, 95% CI:2.64-51.02, p = 0.001) were positively and independently associated with the presence of ASA. AAA tended to be statistically and independently associated with ASA (OR: 2.69, 95% CI:0.97-7.47, p = 0.05). Conclusions. We have demonstrated a higher incidence of mitral/aortic valvular regurgitations, AAA, PFO, and ASD in ASA patients compared to age- and gender-matched control group patients. In addition, we have shown that ASA is significantly and positively associated with mild mitral regurgitation and PFO.en_US
dc.identifier.citationAtak, R., Ileri, M., Ozturk, S., Korkmaz, A., & Yetkin, E. (2019). Echocardiographic findings in patients with atrial septal aneurysm: a prospective case-control study. Cardiology Research and Practice, 2019.en_US
dc.identifier.doi10.1155/2019/3215765en_US
dc.identifier.issn2090-8016en_US
dc.identifier.issn2090-0597en_US
dc.identifier.pmid31061729en_US
dc.identifier.scopus2-s2.0-85065765002en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1155/2019/3215765
dc.identifier.urihttps://hdl.handle.net/20.500.12713/701
dc.identifier.volume2019en_US
dc.identifier.wosWOS:000464682100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYetkin, Ertanen_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofCardiology Research and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEchocardiographic findings in patients with atrial septal aneurysm: a prospective case-control studyen_US
dc.typeArticleen_US

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