The circadian rhythm: an influential soundtrack in the diabetes story

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dc.authoridPrabhakar, Pranav Kumar/0000-0001-8130-1822
dc.authoridTabatabaee, Aliye/0000-0002-9240-7662
dc.authorwosidPrabhakar, Pranav Kumar/G-1416-2010
dc.contributor.authorHariri, Amirali
dc.contributor.authorMirian, Mina
dc.contributor.authorZarrabi, Ali
dc.contributor.authorKohandel, Mohammad
dc.contributor.authorAmini-Pozveh, Maryam
dc.contributor.authorAref, Amir Reza
dc.contributor.authorTabatabaee, Aliye
dc.date.accessioned2024-05-19T14:40:47Z
dc.date.available2024-05-19T14:40:47Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractType 2 Diabetes Mellitus (T2DM) has been the main category of metabolic diseases in recent years due to changes in lifestyle and environmental conditions such as diet and physical activity. On the other hand, the circadian rhythm is one of the most significant biological pathways in humans and other mammals, which is affected by light, sleep, and human activity. However, this cycle is controlled via complicated cellular pathways with feedback loops. It is widely known that changes in the circadian rhythm can alter some metabolic pathways of body cells and could affect the treatment process, particularly for metabolic diseases like T2DM. The aim of this study is to explore the importance of the circadian rhythm in the occurrence of T2DM via reviewing the metabolic pathways involved, their relationship with the circadian rhythm from two perspectives, lifestyle and molecular pathways, and their effect on T2DM pathophysiology. These impacts have been demonstrated in a variety of studies and led to the development of approaches such as time-restricted feeding, chronotherapy (time-specific therapies), and circadian molecule stabilizers.en_US
dc.identifier.doi10.3389/fendo.2023.1156757
dc.identifier.issn1664-2392
dc.identifier.pmid37441501en_US
dc.identifier.scopus2-s2.0-85164738036en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.3389/fendo.2023.1156757
dc.identifier.urihttps://hdl.handle.net/20.500.12713/5016
dc.identifier.volume14en_US
dc.identifier.wosWOS:001025673000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherFrontiers Media Saen_US
dc.relation.ispartofFrontiers In Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectCircadian Rhythmen_US
dc.subjectChronotherapyen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectSleep Disorderen_US
dc.subjectLifestyleen_US
dc.titleThe circadian rhythm: an influential soundtrack in the diabetes storyen_US
dc.typeReview Articleen_US

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