Assessment of biocompatibility of novel TiTaHf-based high entropy alloys for utility in orthopedic implants

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dc.authoridHaluk Çabuk / 0000-0002-1413-2149en_US
dc.authorscopusidHaluk Çabuk / 56400866300
dc.authorwosidHaluk Çabuk / AAL-9654-2020
dc.contributor.authorGürel, Şeyma
dc.contributor.authorNazarahari, Alireza
dc.contributor.authorCanadinç, Demircan
dc.contributor.authorÇabuk, Haluk
dc.contributor.authorBal, Burak
dc.date.accessioned2021-04-14T07:07:38Z
dc.date.available2021-04-14T07:07:38Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractThis paper presents the findings of experimentally observed corrosion response of novel TiTaHf-based high entropy alloys (HEAs) in fetal bovine serum (FBS) to evaluate their biocompatibility in presence of proteins and potential to be used as implant materials. Particularly, TiTaHfNb, TiTaHfNbZr and TiTaHfMoZr HEAs were subjected to static immersion experiments in FBS media, and both the HEA samples and the immersion fluids underwent thorough characterization. The findings presented herein show that Zr and Mo addition to the TiTaHf solid solution increased the total ion release from the resulting HEAs in FBS, while the TiTaHfNb HEA became prominent in terms of biocompatibility owing to the reduced ion release in FBS. Moreover, hydroxy apatite (HA) formation was evident on the surfaces of all three HEAs upon immersion in FBS, indicating the potential of the three TiTaHf-based HEAs to form desired binding with the human bone. Considering the fact that passive oxide layer formation facilitating lower susceptibility to corrosion in long-term applications was also observed in the studied HEAs, further elaboration on their mechanical and biological responses is warranted for the sake of a comprehensive assessment regarding their utility as orthopedic implant materials.en_US
dc.identifier.citationGurel, S., Nazarahari, A., Canadinc, D., Cabuk, H., & Bal, B. (2021). Assessment of Biocompatibility of Novel TiTaHf-based High Entropy Alloys for Utility in Orthopedic Implants. Materials Chemistry and Physics, 124573.en_US
dc.identifier.doi10.1016/j.matchemphys.2021.124573en_US
dc.identifier.issn0254-0584en_US
dc.identifier.scopus2-s2.0-85103686403en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.matchemphys.2021.124573
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1694
dc.identifier.volume266en_US
dc.identifier.wosWOS:000647611000002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorÇabuk, Haluk
dc.language.isoenen_US
dc.publisherElsevier Ltden_US
dc.relation.ispartofMaterials Chemistry and Physicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiocompatibilityen_US
dc.subjectHigh Entropy Alloyen_US
dc.subjectTiTaHfMoZren_US
dc.subjectTiTaHfNben_US
dc.subjectTiTaHfNbZren_US
dc.titleAssessment of biocompatibility of novel TiTaHf-based high entropy alloys for utility in orthopedic implantsen_US
dc.typeArticleen_US

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