The relationship between lesion density change in chest computed tomography and clinical improvement in COVID-19 patients

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dc.authoridIşıl Yurdaışık / 0000-0001-8316-1229en_US
dc.authorscopusidIşıl Yurdaışık / 57211471093
dc.authorwosidIşıl Yurdaışık / AAL-9433-2020
dc.contributor.authorYurdaışık, Işıl
dc.contributor.authorNurili, Fuat
dc.contributor.authorAğırman, Ayşe Gül
dc.contributor.authorAksoy, Süleyman Hilmi
dc.date.accessioned2021-05-18T08:49:27Z
dc.date.available2021-05-18T08:49:27Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractABSTRACT Objective: To evaluate the association of changes in chest computed tomography (CT) lesion densities with clinical improvement in COVID-19 patients. Methods: This was a cross-sectional analysis of hospitalized COVID-19 patients who underwent repeated chest CT. Patients who improved clinically but showed radiological progression were included. Demographic data, presentation complaints, and laboratory results were retrieved from the electronic database of the hospital. Lesion density that was measured in Hounsfield Units (HU) was compred between admission and discharge chest CT scans. Results: Forty patients (21males, mean age 47.4±15.1 years) were included in the analysis. The median white blood cell count and CRP significantly decreased, whereas the median lymphocyte count significantly increased at discharge compared with the admission values. The mean density significantly reduced from admission to discharge. Conclusion: This is the first study in the literature reporting reduction in chest CT lesion densities correlated with clinical and laboratory improvement in COVID-19 patients.en_US
dc.identifier.citationYurdaisik, I., Nurili, F., Agirman, A. G., & Aksoy, S. H. (2021). The Relationship Between Lesion Density Change in Chest CT and Clinical Improvement in COVID-19 Patients. International journal of clinical practice, e14355. Advance online publication. https://doi.org/10.1111/ijcp.14355en_US
dc.identifier.doi10.1111/ijcp.14355en_US
dc.identifier.issn1742-1241en_US
dc.identifier.pmid33974359en_US
dc.identifier.scopus2-s2.0-85106223510en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14355
dc.identifier.urihttps://hdl.handle.net/20.500.12713/1739
dc.identifier.wosWOS:000653240800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYurdaışık, Işıl
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectChest CTen_US
dc.subjectClinical improvementen_US
dc.subjectGround-glass Opacityen_US
dc.subjectHounsfield Unitsen_US
dc.subjectLesion Densityen_US
dc.titleThe relationship between lesion density change in chest computed tomography and clinical improvement in COVID-19 patientsen_US
dc.title.alternativeThe relationship between lesion density change in chest CT and clinical improvement in COVID-19 patientsen_US
dc.typeArticleen_US

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