Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action

dc.authoridGuala, Andrea/0000-0002-5006-8164
dc.authoridPiskin, Senol/0000-0002-8799-9472
dc.authoridAlastruey, Jordi/0000-0003-3742-5259
dc.authoridTerentes-Printzios, Dimitrios/0000-0003-4039-8263
dc.authoridBIANCHINI, ELISABETTA/0000-0002-1827-8866
dc.authorwosidWohlfahrt, Peter/E-6167-2012
dc.authorwosidGuala, Andrea/L-9857-2019
dc.authorwosidPiskin, Senol/F-3741-2019
dc.authorwosidAlastruey, Jordi/HJI-1232-2023
dc.contributor.authorBianchini, Elisabetta
dc.contributor.authorLonnebakken, Mai Tone
dc.contributor.authorWohlfahrt, Peter
dc.contributor.authorPiskin, Senol
dc.contributor.authorTerentes-Printzios, Dimitrios
dc.contributor.authorAlastruey, Jordi
dc.contributor.authorGuala, Andrea
dc.date.accessioned2024-05-19T14:38:55Z
dc.date.available2024-05-19T14:38:55Z
dc.date.issued2023
dc.departmentİstinye Üniversitesien_US
dc.description.abstractMagnetic resonance imaging and computed tomography allow the characterization of arterial state and function with high confidence and thus play a key role in the understanding of arterial aging and its translation into the clinic. Decades of research into the development of innovative imaging sequences and image analysis techniques have led to the identification of a large number of potential biomarkers, some bringing improvement in basic science, others in clinical practice. Nonetheless, the complexity of some of these biomarkers and the image analysis techniques required for their computation hamper their widespread use. In this narrative review, current biomarkers related to aging of the aorta, their founding principles, the sequence, and postprocessing required, and their predictive values for cardiovascular events are summarized. For each biomarker a summary of reference values and reproducibility studies and limitations is provided. The present review, developed in the COST Action VascAgeNet, aims to guide clinicians and technical researchers in the critical understanding of the possibilities offered by these advanced imaging modalities for studying the state and function of the aorta, and their possible clinically relevant relationships with aging.en_US
dc.description.sponsorshipCOST Action [CA18216]; COST (European Cooperation in Science and Technology); Spanish Ministry of Science, Innovation and Universities [IJC2018-037349-I]; la Caixa Foundation [LCF/BQ/PR22/11920008]; European Research Executive Agency; Marie-Sklodowska Curie Actions-Global Individual Fellowship [101038096]; Istinye University, Scientific Research Projects project [2019B1]; Ministry of Health of the Czech Republic [NV 19-09-00125]; British Heart Foundation; Wellcome Engineering and Physical Sciences Research Council Centre for Medical Engineering at King's College London [PG/15/104/31913]; UK Department of Health through the National Institute for Health Research Cardiovascular MedTech Co-Operative at Guy's and St Thomas' National Health Service Foundation Trust [WT 203148/Z/16/Z]; [MIC-2016-019]en_US
dc.description.sponsorshipThis article is based upon work from COST Action CA18216 VascAgeNet, supported by COST (European Cooperation in Science and Technology, www.cost.eu). A. Guala has received funding from Spanish Ministry of Science, Innovation and Universities (IJC2018-037349-I) and from la Caixa Foundation (LCF/BQ/PR22/11920008). S. Piskin has received funding from the European Research Executive Agency, Marie-Sklodowska Curie Actions-Global Individual Fellowship (101038096), and from Istinye University, Scientific Research Projects project (2019B1). P. Wohlfahrt's work was supported by the Ministry of Health of the Czech Republic, grant no. NV 19-09-00125. J. Alastruey was supported by the British Heart Foundation under Grant PG/15/104/31913, the Wellcome Engineering and Physical Sciences Research Council Centre for Medical Engineering at King's College London under Grant WT 203148/Z/16/Z, and the UK Department of Health through the National Institute for Health Research Cardiovascular MedTech Co-Operative at Guy's and St Thomas' National Health Service Foundation Trust under grant MIC-2016-019.en_US
dc.identifier.doi10.1161/JAHA.122.027414
dc.identifier.issn2047-9980
dc.identifier.issue10en_US
dc.identifier.pmid37183857en_US
dc.identifier.scopus2-s2.0-85159741301en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org10.1161/JAHA.122.027414
dc.identifier.urihttps://hdl.handle.net/20.500.12713/4648
dc.identifier.volume12en_US
dc.identifier.wosWOS:001003633600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of the American Heart Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240519_kaen_US
dc.subjectAgingen_US
dc.subjectAortaen_US
dc.subjectArterial Stiffnessen_US
dc.subjectArteriesen_US
dc.subjectCalcificationen_US
dc.titleMagnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Actionen_US
dc.typeReview Articleen_US

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