GAS5 oligonucleotides as therapeutic agents in breast cancer

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dc.authoridMerdan Fayda / 0000-0002-2800-5327en_US
dc.authorscopusidMerdan Fayda / 6506348846
dc.authorwosidMerdan Fayda / AAF-7370-2019
dc.contributor.authorFayda, Merdan
dc.contributor.authorGezer, Uğur
dc.date.accessioned2020-08-29T20:08:23Z
dc.date.available2020-08-29T20:08:23Z
dc.date.issued2016
dc.departmentİstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAlthough relatively less is known about the long non-coding RNA (lncRNA) than the essential protein coding genes, several of them have organismal functions such as lethal knockouts, apoptosis etc. (1,2). Growth arrest specific genes 5 (GAS5) has proven to be pro-apoptotic in breast cancer (BC) cell lines (3). In their paper entitled “The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells” published in March issue of Oncotarget by Pickard and Williams (4) report that an oligonucleotide representing the hormone response element mimic (HREM) sequence within GAS5 alone is able to promote the apoptosis of BC cells similar to fulllength GAS5.en_US
dc.identifier.citationFayda, M., & Gezer, U. (2016). GAS5 oligonucleotides as therapeutic agents in breast cancer. Translational Cancer Research, 5, S567–S568. https://doi.org/10.21037/tcr.2016.08.42en_US
dc.identifier.doi10.21037/tcr.2016.08.42en_US
dc.identifier.endpageS568en_US
dc.identifier.issn2218-676Xen_US
dc.identifier.issn2219-6803en_US
dc.identifier.scopus2-s2.0-84992047458en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageS567en_US
dc.identifier.urihttps://doi.org/10.21037/tcr.2016.08.42
dc.identifier.urihttps://hdl.handle.net/20.500.12713/930
dc.identifier.volume5en_US
dc.identifier.wosWOS:000393310100044en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorFayda, Merdanen_US
dc.language.isoenen_US
dc.publisherAme Publ Coen_US
dc.relation.ispartofTranslational Cancer Researchen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleGAS5 oligonucleotides as therapeutic agents in breast canceren_US
dc.typeEditorialen_US

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